Advancing the 3Rs in bone tissue engineering: emerging in vitro, in silico, and refined in vivo strategies.

Cagle AL, Limberg AK, Anup A, La Croix AE, Hixon KR

DOI: 10.3389/fphys.2026.1811508
Published: 2026
Container: Frontiers in physiology
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.3389/fphys.2026.1811508,
  title = {Advancing the 3Rs in bone tissue engineering: emerging in vitro, in silico, and refined in vivo strategies.},
  author = {Cagle AL and Limberg AK and Anup A and La Croix AE and Hixon KR},
  year = {2026},
  journal = {Frontiers in physiology},
  doi = {10.3389/fphys.2026.1811508},
  url = {https://doi.org/10.3389/fphys.2026.1811508}
}

RIS

TY  - JOUR
TI  - Advancing the 3Rs in bone tissue engineering: emerging in vitro, in silico, and refined in vivo strategies.
AU  - Cagle AL
AU  - Limberg AK
AU  - Anup A
AU  - La Croix AE
AU  - Hixon KR
PY  - 2026
JO  - Frontiers in physiology
DO  - 10.3389/fphys.2026.1811508
UR  - https://doi.org/10.3389/fphys.2026.1811508
ER  -

APA

AL, C., AK, L., A, A., AE, L. C., & KR, H. (2026). Advancing the 3Rs in bone tissue engineering: emerging in vitro, in silico, and refined in vivo strategies.. Frontiers in physiology. https://doi.org/10.3389/fphys.2026.1811508

Source records

pubmed · retrieved 2026-09-27T01:01:55.958Z