Repurposing Heart Failure Therapies in Pulmonary Arterial Hypertension: Mechanistic Rationale, Translational Evidence, and Clinical Perspectives for SGLT2 Inhibitors and Mineralocorticoid Receptor Antagonists

Spyridon Karkoulias, Ioannis Leontsinis, Panagiotis Iliakis, Liza Kallenou, Alexandros Tsiavos, Stergios Soulaidopoulos, Eirini Dri, Eleni Manta, Panayotis K. Vlachakis, Panagiotis Tsioufis, Nikolaos Ktenopoulos, Paschalis Karakasis, Kyriakos Dimitriadis, Polykarpos Christos Patsalis, Christina Chrysohoou, Konstantinos Tsioufis

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DOI: 10.3390/medicina62071345
Published: 2026-07-12
Container: Medicina
Publisher: MDPI AG
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.3390/medicina62071345,
  title = {Repurposing Heart Failure Therapies in Pulmonary Arterial Hypertension: Mechanistic Rationale, Translational Evidence, and Clinical Perspectives for SGLT2 Inhibitors and Mineralocorticoid Receptor Antagonists},
  author = {Spyridon Karkoulias and Ioannis Leontsinis and Panagiotis Iliakis and Liza Kallenou and Alexandros Tsiavos and Stergios Soulaidopoulos and Eirini Dri and Eleni Manta and Panayotis K. Vlachakis and Panagiotis Tsioufis and Nikolaos Ktenopoulos and Paschalis Karakasis and Kyriakos Dimitriadis and Polykarpos Christos Patsalis and Christina Chrysohoou and Konstantinos Tsioufis},
  year = {2026},
  journal = {Medicina},
  doi = {10.3390/medicina62071345},
  url = {https://doi.org/10.3390/medicina62071345}
}

RIS

TY  - JOUR
TI  - Repurposing Heart Failure Therapies in Pulmonary Arterial Hypertension: Mechanistic Rationale, Translational Evidence, and Clinical Perspectives for SGLT2 Inhibitors and Mineralocorticoid Receptor Antagonists
AU  - Spyridon Karkoulias
AU  - Ioannis Leontsinis
AU  - Panagiotis Iliakis
AU  - Liza Kallenou
AU  - Alexandros Tsiavos
AU  - Stergios Soulaidopoulos
AU  - Eirini Dri
AU  - Eleni Manta
AU  - Panayotis K. Vlachakis
AU  - Panagiotis Tsioufis
AU  - Nikolaos Ktenopoulos
AU  - Paschalis Karakasis
AU  - Kyriakos Dimitriadis
AU  - Polykarpos Christos Patsalis
AU  - Christina Chrysohoou
AU  - Konstantinos Tsioufis
PY  - 2026
JO  - Medicina
DO  - 10.3390/medicina62071345
UR  - https://doi.org/10.3390/medicina62071345
ER  -

APA

Karkoulias, S., Leontsinis, I., Iliakis, P., Kallenou, L., Tsiavos, A., Soulaidopoulos, S., Dri, E., Manta, E., Vlachakis, P. K., Tsioufis, P., Ktenopoulos, N., Karakasis, P., Dimitriadis, K., Patsalis, P. C., Chrysohoou, C., & Tsioufis, K. (2026). Repurposing Heart Failure Therapies in Pulmonary Arterial Hypertension: Mechanistic Rationale, Translational Evidence, and Clinical Perspectives for SGLT2 Inhibitors and Mineralocorticoid Receptor Antagonists. Medicina. https://doi.org/10.3390/medicina62071345

Source records

crossref · retrieved 2026-09-27T00:40:46.511Z