Targeting the CAF-GDF15 axis attenuates AKT-mediated mitochondrial rewiring and chemoradiation resistance in esophageal adenocarcinoma

Ningbo Fan, Pinwei Deng, Zhefang Wang, Feng Ju, Lisa Raatz, Oscar Velazquez Camacho, Axel M. Hillmer, Margarete Odenthal, Phuong-Hien Nguyen, Zicheng Lyu, Felix Popp, Seung-Hun Chon, Maarten F. Bijlsma, Romy Ros, Hanneke W. M. van Laarhoven, Alexander Quaas, Jörg Wischhusen, Yue Zhao, Christiane J. Bruns

Open source

DOI: 10.6084/m9.figshare.c.8602312.v1
Published: 2026
Container: Not recorded
Publisher: figshare
Open access: yes

Credibility signals

limited evidence Score 47/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingPublication license: A publication license was supplied: https://creativecommons.org/licenses/by/4.0/legalcode. Presence improves reuse transparency, not research validity. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.6084/m9.figshare.c.8602312.v1,
  title = {Targeting the CAF-GDF15 axis attenuates AKT-mediated mitochondrial rewiring and chemoradiation resistance in esophageal adenocarcinoma},
  author = {Ningbo Fan and Pinwei Deng and Zhefang Wang and Feng Ju and Lisa Raatz and Oscar Velazquez Camacho and Axel M. Hillmer and Margarete Odenthal and Phuong-Hien Nguyen and Zicheng Lyu and Felix Popp and Seung-Hun Chon and Maarten F. Bijlsma and Romy Ros and Hanneke W. M. van Laarhoven and Alexander Quaas and Jörg Wischhusen and Yue Zhao and Christiane J. Bruns},
  year = {2026},
  doi = {10.6084/m9.figshare.c.8602312.v1},
  url = {https://doi.org/10.6084/m9.figshare.c.8602312.v1}
}

RIS

TY  - JOUR
TI  - Targeting the CAF-GDF15 axis attenuates AKT-mediated mitochondrial rewiring and chemoradiation resistance in esophageal adenocarcinoma
AU  - Ningbo Fan
AU  - Pinwei Deng
AU  - Zhefang Wang
AU  - Feng Ju
AU  - Lisa Raatz
AU  - Oscar Velazquez Camacho
AU  - Axel M. Hillmer
AU  - Margarete Odenthal
AU  - Phuong-Hien Nguyen
AU  - Zicheng Lyu
AU  - Felix Popp
AU  - Seung-Hun Chon
AU  - Maarten F. Bijlsma
AU  - Romy Ros
AU  - Hanneke W. M. van Laarhoven
AU  - Alexander Quaas
AU  - Jörg Wischhusen
AU  - Yue Zhao
AU  - Christiane J. Bruns
PY  - 2026
DO  - 10.6084/m9.figshare.c.8602312.v1
UR  - https://doi.org/10.6084/m9.figshare.c.8602312.v1
ER  -

APA

Fan, N., Deng, P., Wang, Z., Ju, F., Raatz, L., Camacho, O. V., Hillmer, A. M., Odenthal, M., Nguyen, P., Lyu, Z., Popp, F., Chon, S., Bijlsma, M. F., Ros, R., Laarhoven, H. W. M. V., Quaas, A., Wischhusen, J., Zhao, Y., & Bruns, C. J. (2026). Targeting the CAF-GDF15 axis attenuates AKT-mediated mitochondrial rewiring and chemoradiation resistance in esophageal adenocarcinoma. https://doi.org/10.6084/m9.figshare.c.8602312.v1

Source records

datacite · retrieved 2026-11-09T07:43:06.433Z