Haplotype-Resolved Genomics Reveals Conserved Chromatin Architecture and Epigenetic Constraints of Human Neocentromeres

Hoyt SJ, Hartley GA, Antopia MC, Tullius TW, Taylor DJ, Tillquist NM, Neph S, Pauloski N, Munson KM, Hoekzema K, Eichler EE, Stergachis AB, Logsdon GA, O’Neill RJ.

Open source

DOI: 10.64898/2025.12.23.696241
Published: 2025-12-25
Container: Not recorded
Publisher: Not recorded
Open access: no

Credibility signals

limited evidence Score 39/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
cautionPublication version: Identified as a preprint; peer review and later versions may change the record. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.64898/2025.12.23.696241,
  title = {Haplotype-Resolved Genomics Reveals Conserved Chromatin Architecture and Epigenetic Constraints of Human Neocentromeres},
  author = {Hoyt SJ and  Hartley GA and  Antopia MC and  Tullius TW and  Taylor DJ and  Tillquist NM and  Neph S and  Pauloski N and  Munson KM and  Hoekzema K and  Eichler EE and  Stergachis AB and  Logsdon GA and  O’Neill RJ.},
  year = {2025},
  doi = {10.64898/2025.12.23.696241},
  url = {https://doi.org/10.64898/2025.12.23.696241}
}

RIS

TY  - JOUR
TI  - Haplotype-Resolved Genomics Reveals Conserved Chromatin Architecture and Epigenetic Constraints of Human Neocentromeres
AU  - Hoyt SJ
AU  -  Hartley GA
AU  -  Antopia MC
AU  -  Tullius TW
AU  -  Taylor DJ
AU  -  Tillquist NM
AU  -  Neph S
AU  -  Pauloski N
AU  -  Munson KM
AU  -  Hoekzema K
AU  -  Eichler EE
AU  -  Stergachis AB
AU  -  Logsdon GA
AU  -  O’Neill RJ.
PY  - 2025
DO  - 10.64898/2025.12.23.696241
UR  - https://doi.org/10.64898/2025.12.23.696241
ER  -

APA

SJ, H., GA, H., MC, A., TW, T., DJ, T., NM, T., S, N., N, P., KM, M., K, H., EE, E., AB, S., GA, L., & RJ., O. (2025). Haplotype-Resolved Genomics Reveals Conserved Chromatin Architecture and Epigenetic Constraints of Human Neocentromeres. https://doi.org/10.64898/2025.12.23.696241

Source records

europe-pmc · retrieved 2026-09-27T02:46:40.179Z