Local and circulating cytotoxic CD4⁺ T cells are early markers of disease activity in pediatric Crohn’s disease

Veronika Niederlova, Kyle Kimler, Hengqi Betty Zheng, Marc Elosua Bayes, Rose Hedderman, Paula Keskula, Iva Pacakova, Jan Vecek, Joshua de Sousa Casal, Andrew Kwong, Leonard Nettey, Zoë Steier, Katarína Kováčová, Brandi Bratrude, Jillian Zavistaski, Wei Keat Lim, Andrea T. Hooper, Scott MacDonnell, Nathalie Fiaschi, Zaruhi Hovhannisyan, Ghassan Wahbeh, David Suskind, Lusine Ambartsumyan, Dale Lee, Jan Dobeš, Scott B. Snapper, Ondrej Stepanek, Alex K. Shalek, Leslie S. Kean, Jose Ordovas-Montanes

Open source

DOI: 10.64898/2026.06.16.26354238
Published: 2026-06-26
Container: Not recorded
Publisher: openRxiv
Open access: unknown

Credibility signals

uncertain Score 60/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

supportingDOI registered: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
supportingDOI resolves: A matching record was returned by Crossref. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredOpen access status: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
cautionPublication version: Identified as a preprint; peer review and later versions may change the record. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
supportingMetadata completeness: All 6 scored descriptive metadata groups are present. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.64898/2026.06.16.26354238,
  title = {Local and circulating cytotoxic CD4⁺ T cells are early markers of disease activity in pediatric Crohn’s disease},
  author = {Veronika Niederlova and Kyle Kimler and Hengqi Betty Zheng and Marc Elosua Bayes and Rose Hedderman and Paula Keskula and Iva Pacakova and Jan Vecek and Joshua de Sousa Casal and Andrew Kwong and Leonard Nettey and Zoë Steier and Katarína Kováčová and Brandi Bratrude and Jillian Zavistaski and Wei Keat Lim and Andrea T. Hooper and Scott MacDonnell and Nathalie Fiaschi and Zaruhi Hovhannisyan and Ghassan Wahbeh and David Suskind and Lusine Ambartsumyan and Dale Lee and Jan Dobeš and Scott B. Snapper and Ondrej Stepanek and Alex K. Shalek and Leslie S. Kean and Jose Ordovas-Montanes},
  year = {2026},
  doi = {10.64898/2026.06.16.26354238},
  url = {https://doi.org/10.64898/2026.06.16.26354238}
}

RIS

TY  - JOUR
TI  - Local and circulating cytotoxic CD4⁺ T cells are early markers of disease activity in pediatric Crohn’s disease
AU  - Veronika Niederlova
AU  - Kyle Kimler
AU  - Hengqi Betty Zheng
AU  - Marc Elosua Bayes
AU  - Rose Hedderman
AU  - Paula Keskula
AU  - Iva Pacakova
AU  - Jan Vecek
AU  - Joshua de Sousa Casal
AU  - Andrew Kwong
AU  - Leonard Nettey
AU  - Zoë Steier
AU  - Katarína Kováčová
AU  - Brandi Bratrude
AU  - Jillian Zavistaski
AU  - Wei Keat Lim
AU  - Andrea T. Hooper
AU  - Scott MacDonnell
AU  - Nathalie Fiaschi
AU  - Zaruhi Hovhannisyan
AU  - Ghassan Wahbeh
AU  - David Suskind
AU  - Lusine Ambartsumyan
AU  - Dale Lee
AU  - Jan Dobeš
AU  - Scott B. Snapper
AU  - Ondrej Stepanek
AU  - Alex K. Shalek
AU  - Leslie S. Kean
AU  - Jose Ordovas-Montanes
PY  - 2026
DO  - 10.64898/2026.06.16.26354238
UR  - https://doi.org/10.64898/2026.06.16.26354238
ER  -

APA

Niederlova, V., Kimler, K., Zheng, H. B., Bayes, M. E., Hedderman, R., Keskula, P., Pacakova, I., Vecek, J., Casal, J. D. S., Kwong, A., Nettey, L., Steier, Z., Kováčová, K., Bratrude, B., Zavistaski, J., Lim, W. K., Hooper, A. T., MacDonnell, S., Fiaschi, N., Hovhannisyan, Z., Wahbeh, G., Suskind, D., Ambartsumyan, L., Lee, D., Dobeš, J., Snapper, S. B., Stepanek, O., Shalek, A. K., Kean, L. S., & Ordovas-Montanes, J. (2026). Local and circulating cytotoxic CD4⁺ T cells are early markers of disease activity in pediatric Crohn’s disease. https://doi.org/10.64898/2026.06.16.26354238

Source records

crossref · retrieved 2026-09-27T12:47:20.353Z