A multi-organ spatial metabolomic atlas of exercising mice reveals neuronal Complex I as a convergent and sufficient axis for tau pathology reduction in PS19

Terrymar Medina, Sadi Quiñones, Zizhen Liu, Lei Wu, Borhane Ziani, Cameron Shedlock, Xin Ma, Alison Ryan, Reece Larson, Charles M. Soto, Vicenzo Barco-Caiaffa, Ann Titus, Kangjin Wong, Nidhi Rao, Sophia Florea, Miguel A. Gutierrez-Monreal, Gordon S. Mitchell, Craig W. Vander Kooi, Matthew S. Gentry, Navdeep S. Chandel, Karyn A. Esser, Ramon C. Sun

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DOI
10.64898/2026.06.16.732673
Published
2026-06-22
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Not recorded
Publisher
openRxiv
Open access
unknown

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BibTeX

@article{allodium:10.64898/2026.06.16.732673,
  title = {A multi-organ spatial metabolomic atlas of exercising mice reveals neuronal Complex I as a convergent and sufficient axis for tau pathology reduction in PS19},
  author = {Terrymar Medina and Sadi Quiñones and Zizhen Liu and Lei Wu and Borhane Ziani and Cameron Shedlock and Xin Ma and Alison Ryan and Reece Larson and Charles M. Soto and Vicenzo Barco-Caiaffa and Ann Titus and Kangjin Wong and Nidhi Rao and Sophia Florea and Miguel A. Gutierrez-Monreal and Gordon S. Mitchell and Craig W. Vander Kooi and Matthew S. Gentry and Navdeep S. Chandel and Karyn A. Esser and Ramon C. Sun},
  year = {2026},
  doi = {10.64898/2026.06.16.732673},
  url = {https://doi.org/10.64898/2026.06.16.732673}
}

RIS

TY  - JOUR
TI  - A multi-organ spatial metabolomic atlas of exercising mice reveals neuronal Complex I as a convergent and sufficient axis for tau pathology reduction in PS19
AU  - Terrymar Medina
AU  - Sadi Quiñones
AU  - Zizhen Liu
AU  - Lei Wu
AU  - Borhane Ziani
AU  - Cameron Shedlock
AU  - Xin Ma
AU  - Alison Ryan
AU  - Reece Larson
AU  - Charles M. Soto
AU  - Vicenzo Barco-Caiaffa
AU  - Ann Titus
AU  - Kangjin Wong
AU  - Nidhi Rao
AU  - Sophia Florea
AU  - Miguel A. Gutierrez-Monreal
AU  - Gordon S. Mitchell
AU  - Craig W. Vander Kooi
AU  - Matthew S. Gentry
AU  - Navdeep S. Chandel
AU  - Karyn A. Esser
AU  - Ramon C. Sun
PY  - 2026
DO  - 10.64898/2026.06.16.732673
UR  - https://doi.org/10.64898/2026.06.16.732673
ER  - 

APA

Medina, T., Quiñones, S., Liu, Z., Wu, L., Ziani, B., Shedlock, C., Ma, X., Ryan, A., Larson, R., Soto, C. M., Barco-Caiaffa, V., Titus, A., Wong, K., Rao, N., Florea, S., Gutierrez-Monreal, M. A., Mitchell, G. S., Kooi, C. W. V., Gentry, M. S., Chandel, N. S., Esser, K. A., & Sun, R. C. (2026). A multi-organ spatial metabolomic atlas of exercising mice reveals neuronal Complex I as a convergent and sufficient axis for tau pathology reduction in PS19. https://doi.org/10.64898/2026.06.16.732673

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