Model Validation Protocols for Machine Learning in Small Molecule Drug Discovery

Seal S, Zalte AS, Araripe DA, Gomes RA, Korani D, Shekhar M, Siramshetty VB, Patra A, Mou Z, Yu X, Kuhn D, Weskamp N, Ash J, Cheng AC, Fang C, Price D, Aldeghi M, Rodríguez-Pérez R, Clevert D, Engkvist O, Deibler K, Rouquie D, Reutlinger M, Richmond NJ, Ainsley J, Ledeboer M, Green WH, Bender A, Wognum C.

Open source

DOI
10.64898/2026.08.19.745868
Published
2026-08-24
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Open access
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BibTeX

@article{allodium:10.64898/2026.08.19.745868,
  title = {Model Validation Protocols for Machine Learning in Small Molecule Drug Discovery},
  author = {Seal S and  Zalte AS and  Araripe DA and  Gomes RA and  Korani D and  Shekhar M and  Siramshetty VB and  Patra A and  Mou Z and  Yu X and  Kuhn D and  Weskamp N and  Ash J and  Cheng AC and  Fang C and  Price D and  Aldeghi M and  Rodríguez-Pérez R and  Clevert D and  Engkvist O and  Deibler K and  Rouquie D and  Reutlinger M and  Richmond NJ and  Ainsley J and  Ledeboer M and  Green WH and  Bender A and  Wognum C.},
  year = {2026},
  doi = {10.64898/2026.08.19.745868},
  url = {https://doi.org/10.64898/2026.08.19.745868}
}

RIS

TY  - JOUR
TI  - Model Validation Protocols for Machine Learning in Small Molecule Drug Discovery
AU  - Seal S
AU  -  Zalte AS
AU  -  Araripe DA
AU  -  Gomes RA
AU  -  Korani D
AU  -  Shekhar M
AU  -  Siramshetty VB
AU  -  Patra A
AU  -  Mou Z
AU  -  Yu X
AU  -  Kuhn D
AU  -  Weskamp N
AU  -  Ash J
AU  -  Cheng AC
AU  -  Fang C
AU  -  Price D
AU  -  Aldeghi M
AU  -  Rodríguez-Pérez R
AU  -  Clevert D
AU  -  Engkvist O
AU  -  Deibler K
AU  -  Rouquie D
AU  -  Reutlinger M
AU  -  Richmond NJ
AU  -  Ainsley J
AU  -  Ledeboer M
AU  -  Green WH
AU  -  Bender A
AU  -  Wognum C.
PY  - 2026
DO  - 10.64898/2026.08.19.745868
UR  - https://doi.org/10.64898/2026.08.19.745868
ER  - 

APA

S, S., AS, Z., DA, A., RA, G., D, K., M, S., VB, S., A, P., Z, M., X, Y., D, K., N, W., J, A., AC, C., C, F., D, P., M, A., R, R., D, C., O, E., K, D., D, R., M, R., NJ, R., J, A., M, L., WH, G., A, B., & C., W. (2026). Model Validation Protocols for Machine Learning in Small Molecule Drug Discovery. https://doi.org/10.64898/2026.08.19.745868

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