Rare coding variation implicates thirteen genes in bipolar disorder across 232,536 individuals from global populations.

Liao C, Ye R, Sealock JM, Boltz T, Ivankovic F, Finucane H, Howrigan D, Liu YC, Satterstrom FK, Hassan A, Alemayehu M, Gichuru S, Mwende RM, Newton CRJC, Koen N, Zingela Z, Diaz-Zuluaga AM, Ramirez-Diaz AM, Reus VI, Teshiba T, Palotie A, Hämäläinen E, Pietiläinen O, Lind PA, Siskind DJ, Hickie IB, Morales-Cedillo P, Jiménez-Pavón J, Sanabrais-Jiménez MA, Sotelo-Ramírez CE, Hahn E, Nguyen VP, Karlson E, Chang CE, Chen HC, Alda M, Landén M, Smoller JW, Craddock N, Vawter MP, Curtis D, McQuillin A, Kahn RS, Ophoff RA, Vreeker A, Hultman C, Sullivan PF, Talkowski ME, Blackwood DH, McIntosh A, Pulver AE, Cohen B, Adolfsson R, Reif A, Goes F, Yolken R, Corvin AP, Morris DW, BIPEX Collection Scientists, Cerrato F, Chapman SB, Cusick C, Guo Z, Olivares AM, Rouleau GA, Viswanath B, Kuo PH, Nguyen VT, Ta TMT, Camarena B, Pato CN, Pato MT, Medland SE, Freimer N, Loohuis LO, Lopez-Jaramillo C, Stroud R 2nd, Atwoli L, Dickens A, Koenen KC, Kariuki SM, Teferra S, Stein DJ, Ayub M, Knowles JA, Daly MJ, Huang H, Neale BM

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DOI
10.64898/2026.09.30.26364416
Published
2026 Oct 5
Container
medRxiv : the preprint server for health sciences
Publisher
Not recorded
Open access
yes

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BibTeX

@article{allodium:10.64898/2026.09.30.26364416,
  title = {Rare coding variation implicates thirteen genes in bipolar disorder across 232,536 individuals from global populations.},
  author = {Liao C and Ye R and Sealock JM and Boltz T and Ivankovic F and Finucane H and Howrigan D and Liu YC and Satterstrom FK and Hassan A and Alemayehu M and Gichuru S and Mwende RM and Newton CRJC and Koen N and Zingela Z and Diaz-Zuluaga AM and Ramirez-Diaz AM and Reus VI and Teshiba T and Palotie A and Hämäläinen E and Pietiläinen O and Lind PA and Siskind DJ and Hickie IB and Morales-Cedillo P and Jiménez-Pavón J and Sanabrais-Jiménez MA and Sotelo-Ramírez CE and Hahn E and Nguyen VP and Karlson E and Chang CE and Chen HC and Alda M and Landén M and Smoller JW and Craddock N and Vawter MP and Curtis D and McQuillin A and Kahn RS and Ophoff RA and Vreeker A and Hultman C and Sullivan PF and Talkowski ME and Blackwood DH and McIntosh A and Pulver AE and Cohen B and Adolfsson R and Reif A and Goes F and Yolken R and Corvin AP and Morris DW and BIPEX Collection Scientists and Cerrato F and Chapman SB and Cusick C and Guo Z and Olivares AM and Rouleau GA and Viswanath B and Kuo PH and Nguyen VT and Ta TMT and Camarena B and Pato CN and Pato MT and Medland SE and Freimer N and Loohuis LO and Lopez-Jaramillo C and Stroud R 2nd and Atwoli L and Dickens A and Koenen KC and Kariuki SM and Teferra S and Stein DJ and Ayub M and Knowles JA and Daly MJ and Huang H and Neale BM},
  year = {2026},
  journal = {medRxiv : the preprint server for health sciences},
  doi = {10.64898/2026.09.30.26364416},
  url = {https://doi.org/10.64898/2026.09.30.26364416}
}

RIS

TY  - JOUR
TI  - Rare coding variation implicates thirteen genes in bipolar disorder across 232,536 individuals from global populations.
AU  - Liao C
AU  - Ye R
AU  - Sealock JM
AU  - Boltz T
AU  - Ivankovic F
AU  - Finucane H
AU  - Howrigan D
AU  - Liu YC
AU  - Satterstrom FK
AU  - Hassan A
AU  - Alemayehu M
AU  - Gichuru S
AU  - Mwende RM
AU  - Newton CRJC
AU  - Koen N
AU  - Zingela Z
AU  - Diaz-Zuluaga AM
AU  - Ramirez-Diaz AM
AU  - Reus VI
AU  - Teshiba T
AU  - Palotie A
AU  - Hämäläinen E
AU  - Pietiläinen O
AU  - Lind PA
AU  - Siskind DJ
AU  - Hickie IB
AU  - Morales-Cedillo P
AU  - Jiménez-Pavón J
AU  - Sanabrais-Jiménez MA
AU  - Sotelo-Ramírez CE
AU  - Hahn E
AU  - Nguyen VP
AU  - Karlson E
AU  - Chang CE
AU  - Chen HC
AU  - Alda M
AU  - Landén M
AU  - Smoller JW
AU  - Craddock N
AU  - Vawter MP
AU  - Curtis D
AU  - McQuillin A
AU  - Kahn RS
AU  - Ophoff RA
AU  - Vreeker A
AU  - Hultman C
AU  - Sullivan PF
AU  - Talkowski ME
AU  - Blackwood DH
AU  - McIntosh A
AU  - Pulver AE
AU  - Cohen B
AU  - Adolfsson R
AU  - Reif A
AU  - Goes F
AU  - Yolken R
AU  - Corvin AP
AU  - Morris DW
AU  - BIPEX Collection Scientists
AU  - Cerrato F
AU  - Chapman SB
AU  - Cusick C
AU  - Guo Z
AU  - Olivares AM
AU  - Rouleau GA
AU  - Viswanath B
AU  - Kuo PH
AU  - Nguyen VT
AU  - Ta TMT
AU  - Camarena B
AU  - Pato CN
AU  - Pato MT
AU  - Medland SE
AU  - Freimer N
AU  - Loohuis LO
AU  - Lopez-Jaramillo C
AU  - Stroud R 2nd
AU  - Atwoli L
AU  - Dickens A
AU  - Koenen KC
AU  - Kariuki SM
AU  - Teferra S
AU  - Stein DJ
AU  - Ayub M
AU  - Knowles JA
AU  - Daly MJ
AU  - Huang H
AU  - Neale BM
PY  - 2026
JO  - medRxiv : the preprint server for health sciences
DO  - 10.64898/2026.09.30.26364416
UR  - https://doi.org/10.64898/2026.09.30.26364416
ER  -

APA

C, L., R, Y., JM, S., T, B., F, I., H, F., D, H., YC, L., FK, S., A, H., M, A., S, G., RM, M., CRJC, N., N, K., Z, Z., AM, D., AM, R., VI, R., T, T., A, P., E, H., O, P., PA, L., DJ, S., IB, H., P, M., J, J., MA, S., CE, S., E, H., VP, N., E, K., CE, C., HC, C., M, A., M, L., JW, S., N, C., MP, V., D, C., A, M., RS, K., RA, O., A, V., C, H., PF, S., ME, T., DH, B., A, M., AE, P., B, C., R, A., A, R., F, G., R, Y., AP, C., DW, M., Scientists, B. C., F, C., SB, C., C, C., Z, G., AM, O., GA, R., B, V., PH, K., VT, N., TMT, T., B, C., CN, P., MT, P., SE, M., N, F., LO, L., C, L., 2nd, S. R., L, A., A, D., KC, K., SM, K., S, T., DJ, S., M, A., JA, K., MJ, D., H, H., & BM, N. (2026). Rare coding variation implicates thirteen genes in bipolar disorder across 232,536 individuals from global populations.. medRxiv : the preprint server for health sciences. https://doi.org/10.64898/2026.09.30.26364416

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