GAT1508, a selective neuronal GIRK1/2 activator, exhibits superior antiepileptic efficacy and synergizes with cannabidiol.

Simhadri J, Zorn A, Wang L, Kawano T, Cordero-Ruiz N, Vagiaki L, Parvaiz N, Zaka M, Cantwell L, Chan KW, Santa-Cruz A, Dadiotis E, Rivera N, Felix W, Thakur GA, Manetsch R, Plant LD, Sidiropoulou K, Cui M, Skiniotis G, Logothetis DE, Smirnakis SM

Open source

DOI
10.64898/2026.10.14.758970
Published
2026 Oct 16
Container
bioRxiv : the preprint server for biology
Publisher
Not recorded
Open access
yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

Cite this work

BibTeX

@article{allodium:10.64898/2026.10.14.758970,
  title = {GAT1508, a selective neuronal GIRK1/2 activator, exhibits superior antiepileptic efficacy and synergizes with cannabidiol.},
  author = {Simhadri J and Zorn A and Wang L and Kawano T and Cordero-Ruiz N and Vagiaki L and Parvaiz N and Zaka M and Cantwell L and Chan KW and Santa-Cruz A and Dadiotis E and Rivera N and Felix W and Thakur GA and Manetsch R and Plant LD and Sidiropoulou K and Cui M and Skiniotis G and Logothetis DE and Smirnakis SM},
  year = {2026},
  journal = {bioRxiv : the preprint server for biology},
  doi = {10.64898/2026.10.14.758970},
  url = {https://doi.org/10.64898/2026.10.14.758970}
}

RIS

TY  - JOUR
TI  - GAT1508, a selective neuronal GIRK1/2 activator, exhibits superior antiepileptic efficacy and synergizes with cannabidiol.
AU  - Simhadri J
AU  - Zorn A
AU  - Wang L
AU  - Kawano T
AU  - Cordero-Ruiz N
AU  - Vagiaki L
AU  - Parvaiz N
AU  - Zaka M
AU  - Cantwell L
AU  - Chan KW
AU  - Santa-Cruz A
AU  - Dadiotis E
AU  - Rivera N
AU  - Felix W
AU  - Thakur GA
AU  - Manetsch R
AU  - Plant LD
AU  - Sidiropoulou K
AU  - Cui M
AU  - Skiniotis G
AU  - Logothetis DE
AU  - Smirnakis SM
PY  - 2026
JO  - bioRxiv : the preprint server for biology
DO  - 10.64898/2026.10.14.758970
UR  - https://doi.org/10.64898/2026.10.14.758970
ER  - 

APA

J, S., A, Z., L, W., T, K., N, C., L, V., N, P., M, Z., L, C., KW, C., A, S., E, D., N, R., W, F., GA, T., R, M., LD, P., K, S., M, C., G, S., DE, L., & SM, S. (2026). GAT1508, a selective neuronal GIRK1/2 activator, exhibits superior antiepileptic efficacy and synergizes with cannabidiol.. bioRxiv : the preprint server for biology. https://doi.org/10.64898/2026.10.14.758970

Source records