Too early for LATE? Age at onset is associated with the clinical and neuroimaging expression of limbic-predominant age- related TDP-43 pathology in Alzheimer's disease.

Zhu N, La Joie R, Allen IE, Lin M, Fischer DL, Soleimani-Meigooni DN, Rosen HJ, Gorno-Tempini ML, Miller Z, Perry DC, Kramer J, Possin KL, Cobigo Y, Melgoza L, Lago AL, Yokoyama J, Yballa C, Blazhenets G, Miller BL, Grinberg LT, Seeley WW, Spina S, Rabinovici GD

Open source

DOI: 10.64898/2026.10.15.26365384
Published: 2026 Oct 20
Container: medRxiv : the preprint server for health sciences
Publisher: Not recorded
Open access: yes

Credibility signals

limited evidence Score 45/100 under policy 1.0.0. This is a metadata assessment, not a judgment of the paper's conclusions.

Show all credibility signals

cautionDOI registered: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
cautionDOI resolves: No matching Crossref record was present in this response. Source: Crossref; license: CC0 metadata
not scoredDirectory of Open Access Journals: No matching DOAJ record was present in this response. No allow-list match; this is not evidence of low credibility. Source: DOAJ; license: CC0
not scoredMEDLINE indexed: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredOpenAlex core source: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredKnown publisher allow-list: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredROR affiliation: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredRetraction Watch retraction: No retraction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch expression of concern: No expression of concern notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch correction: No correction notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
not scoredRetraction Watch reinstatement: No reinstatement notice matched this DOI in the deployed snapshot. No matching event found; coverage may be incomplete. Source: Retraction Watch; license: CC BY 4.0
supportingOpen access status: Normalized open-access status: open. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
not scoredPublication license: Not checked or no result supplied; no credibility inference made. Source: No authority result supplied; license: Unknown
not scoredPublication version: A publication version was supplied but is not scored. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer
cautionMetadata completeness: 5 of 6 scored descriptive metadata groups are present; missing fields increase uncertainty. Source: Normalized work metadata; license: Caller-provided; provenance license not supplied to scorer

Cite this work

BibTeX

@article{allodium:10.64898/2026.10.15.26365384,
  title = {Too early for LATE? Age at onset is associated with the clinical and neuroimaging expression of limbic-predominant age- related TDP-43 pathology in Alzheimer's disease.},
  author = {Zhu N and La Joie R and Allen IE and Lin M and Fischer DL and Soleimani-Meigooni DN and Rosen HJ and Gorno-Tempini ML and Miller Z and Perry DC and Kramer J and Possin KL and Cobigo Y and Melgoza L and Lago AL and Yokoyama J and Yballa C and Blazhenets G and Miller BL and Grinberg LT and Seeley WW and Spina S and Rabinovici GD},
  year = {2026},
  journal = {medRxiv : the preprint server for health sciences},
  doi = {10.64898/2026.10.15.26365384},
  url = {https://doi.org/10.64898/2026.10.15.26365384}
}

RIS

TY  - JOUR
TI  - Too early for LATE? Age at onset is associated with the clinical and neuroimaging expression of limbic-predominant age- related TDP-43 pathology in Alzheimer's disease.
AU  - Zhu N
AU  - La Joie R
AU  - Allen IE
AU  - Lin M
AU  - Fischer DL
AU  - Soleimani-Meigooni DN
AU  - Rosen HJ
AU  - Gorno-Tempini ML
AU  - Miller Z
AU  - Perry DC
AU  - Kramer J
AU  - Possin KL
AU  - Cobigo Y
AU  - Melgoza L
AU  - Lago AL
AU  - Yokoyama J
AU  - Yballa C
AU  - Blazhenets G
AU  - Miller BL
AU  - Grinberg LT
AU  - Seeley WW
AU  - Spina S
AU  - Rabinovici GD
PY  - 2026
JO  - medRxiv : the preprint server for health sciences
DO  - 10.64898/2026.10.15.26365384
UR  - https://doi.org/10.64898/2026.10.15.26365384
ER  -

APA

N, Z., R, L. J., IE, A., M, L., DL, F., DN, S., HJ, R., ML, G., Z, M., DC, P., J, K., KL, P., Y, C., L, M., AL, L., J, Y., C, Y., G, B., BL, M., LT, G., WW, S., S, S., & GD, R. (2026). Too early for LATE? Age at onset is associated with the clinical and neuroimaging expression of limbic-predominant age- related TDP-43 pathology in Alzheimer's disease.. medRxiv : the preprint server for health sciences. https://doi.org/10.64898/2026.10.15.26365384

Source records

pubmed · retrieved 2026-11-10T12:50:45.243Z