Deep mutational scanning reveals pharmacologically relevant insights into TYK2 signaling and disease

Conor J Howard, Nathan S Abell, Robert R Warneford-Thomson, Eden Mahdavi, Alan L Su, Carmen Resnick, Nabil Mohammed, Erin M Thompson, Emily R Holzinger, Katrina Catalano, Abhay Hukku, Gabriel A Mintier, Morgan MacKenzie, Bryan L Jiang, Dora Barbosa Rabago, Angela Chan, Carolindah Ntimi, Kaitlyn N Weiler, Stephen C Wilson, Joseph C Maranville, Payal R Sheth, Robert M Plenge, Sriram Kosuri, Diane E Dickel

Open source

DOI: 10.7554/elife.110149
Published: 2026-06-10
Container: eLife
Publisher: eLife Sciences Publications, Ltd
Open access: unknown

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Cite this work

BibTeX

@article{allodium:10.7554/elife.110149,
  title = {Deep mutational scanning reveals pharmacologically relevant insights into TYK2 signaling and disease},
  author = {Conor J Howard and Nathan S Abell and Robert R Warneford-Thomson and Eden Mahdavi and Alan L Su and Carmen Resnick and Nabil Mohammed and Erin M Thompson and Emily R Holzinger and Katrina Catalano and Abhay Hukku and Gabriel A Mintier and Morgan MacKenzie and Bryan L Jiang and Dora Barbosa Rabago and Angela Chan and Carolindah Ntimi and Kaitlyn N Weiler and Stephen C Wilson and Joseph C Maranville and Payal R Sheth and Robert M Plenge and Sriram Kosuri and Diane E Dickel},
  year = {2026},
  journal = {eLife},
  doi = {10.7554/elife.110149},
  url = {https://doi.org/10.7554/elife.110149}
}

RIS

TY  - JOUR
TI  - Deep mutational scanning reveals pharmacologically relevant insights into TYK2 signaling and disease
AU  - Conor J Howard
AU  - Nathan S Abell
AU  - Robert R Warneford-Thomson
AU  - Eden Mahdavi
AU  - Alan L Su
AU  - Carmen Resnick
AU  - Nabil Mohammed
AU  - Erin M Thompson
AU  - Emily R Holzinger
AU  - Katrina Catalano
AU  - Abhay Hukku
AU  - Gabriel A Mintier
AU  - Morgan MacKenzie
AU  - Bryan L Jiang
AU  - Dora Barbosa Rabago
AU  - Angela Chan
AU  - Carolindah Ntimi
AU  - Kaitlyn N Weiler
AU  - Stephen C Wilson
AU  - Joseph C Maranville
AU  - Payal R Sheth
AU  - Robert M Plenge
AU  - Sriram Kosuri
AU  - Diane E Dickel
PY  - 2026
JO  - eLife
DO  - 10.7554/elife.110149
UR  - https://doi.org/10.7554/elife.110149
ER  -

APA

Howard, C. J., Abell, N. S., Warneford-Thomson, R. R., Mahdavi, E., Su, A. L., Resnick, C., Mohammed, N., Thompson, E. M., Holzinger, E. R., Catalano, K., Hukku, A., Mintier, G. A., MacKenzie, M., Jiang, B. L., Rabago, D. B., Chan, A., Ntimi, C., Weiler, K. N., Wilson, S. C., Maranville, J. C., Sheth, P. R., Plenge, R. M., Kosuri, S., & Dickel, D. E. (2026). Deep mutational scanning reveals pharmacologically relevant insights into TYK2 signaling and disease. eLife. https://doi.org/10.7554/elife.110149

Source records

crossref · retrieved 2026-09-27T00:08:16.418Z