Fields · Life Sciences · Biochemistry, Genetics and Molecular Biology · Genetics

Inflammatory Bowel Disease

This cluster of papers explores the genetics, epidemiology, pathogenesis, and treatment of inflammatory bowel diseases such as Crohn's disease and ulcerative colitis. It covers topics such as host-microbe interactions, genetic susceptibility loci, immune system involvement, therapeutic targets, and the global burden of these diseases.

123,433 works

Papers listed on taxonomy pages are the top few works per node from the OpenAlex snapshot. That list is not exhaustive and is not an endorsement. The topic map and the journal registry remain separate: there is still no authoritative topic-to-venue or topic-to-organization edge. Search is a lexical lookup, not a claim that a venue publishes a topic.

Most cited

  1. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

    Yasunori Ogura, Denise K. Bonen, Naohiro Inohara, Dan L. Nicolae · 2001 · Nature · 5,036 citations

  2. Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

    Luke Jostins, Stephan Ripke, Rinse K. Weersma, Richard H. Duerr · 2012 · Nature · 4,920 citations

  3. Unravelling the pathogenesis of inflammatory bowel disease

    Ramnik J. Xavier, Daniel K. Podolsky · 2007 · Nature · 4,381 citations

  4. Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial

    Stephen B. Hanauer, Brian G. Feagan, Gary R. Lichtenstein, Lloyd Mayer · 2002 · The Lancet · 4,181 citations

  5. Infliximab for Induction and Maintenance Therapy for Ulcerative Colitis

    Paul Rutgeerts, William J. Sandborn, Brian G. Feagan, Walter Reinisch · 2005 · New England Journal of Medicine · 3,914 citations

  6. Ulcerative colitis

    Ryan C. Ungaro, Saurabh Mehandru, Patrick B. Allen, Laurent Peyrin‐Biroulet · 2016 · The Lancet · 3,549 citations

Most recent

  1. Refractory Chronic Inflammatory Bowel Disease in Childhood and Adolescence: Options in Primary Non-Response or Secondary Treatment Failure.

    Rommel Fa, Christa Bergheim, Ralph Melchior, Krause Tr · 2026 · PubMed · 0 citations

  2. Nutrition in inflammatory bowel diseases

    Kalina Grivcheva Stardelova, Fana Lichoska Josifovikj, Filip Nikolov, Dzem Adem · 2026 · DOAJ (DOAJ: Directory of Open Access Journals) · 0 citations

  3. Rosuvastatin and engeletin ameliorate acetic acid-induced ulcerative colitis through modulation of TXNIP/NLRP3-related inflammatory signaling pathway

    Thanaa A. El-Masry, Sally E. Abu-Risha, Walaa A. Negm, Eman A. Kamal · 2026 · Figshare · 0 citations

  4. Food choices and beliefs in adults with inflammatory bowel disease in Sweden

    Sara Andersson, Katarina M. Korwel, Klas Sjöberg, Katarina Pihl Lesnovska · 2026 · BMC Gastroenterology · 0 citations

  5. Predictors of time to surgical recurrence after ileal or ileocolonic resection in Crohn’s disease: role of integrin αvβ6 and development of a predictive nomogram

    Haiting Xie, Ye Yao, Xiujun Liao, Yurong Jiao · 2026 · Updates in Surgery · 0 citations

  6. Preventive administration of verapamil attenuates dextran sulfate sodium‑induced colitis in mice

    Natsuki Ota, Keisuke Sato, Ryosuke Tatsunami · 2026 · Experimental and Therapeutic Medicine · 0 citations

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