Parkinson's Disease Mechanisms and Treatments
This cluster of papers explores the pathophysiology, clinical features, diagnosis, genetic risk factors, and management of Parkinson's disease. It delves into the role of a-synuclein, neurodegeneration, dopaminergic neurons, oxidative stress, and mitochondrial dysfunction in the development and progression of the disease. Additionally, it discusses the non-motor symptoms and Lewy body pathology associated with Parkinson's disease.
Papers listed on taxonomy pages are the top few works per node from the OpenAlex snapshot. That list is not exhaustive and is not an endorsement. The topic map and the journal registry remain separate: there is still no authoritative topic-to-venue or topic-to-organization edge. Search is a lexical lookup, not a claim that a venue publishes a topic.
Most cited
- Staging of brain pathology related to sporadic Parkinson’s disease
- Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases.
- α-Synuclein in Lewy bodies
- Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease
- Movement Disorder Society‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS): Scale presentation and clinimetric testing results
- MDS clinical diagnostic criteria for Parkinson's disease
Most recent
- Phenomic characterization of C. elegans orthologs of Parkinson's disease-associated genes
- Dual effect of α-synuclein disease variants on condensate formation
- High frequency of LRRK2 p.Gly2019Ser in Moroccan Parkinson’s disease: RFLP as a reliable genotyping approach
- Shared Metabolic–Proteinopathy Axis in Alzheimer's Disease and Parkinson's Disease: Evidence for a Convergent but Not Identical Disease Spectrum
- Transcriptome Sequencing Reveals Molecular Characteristics of Spinal Cord Degeneration in MPTP-Induced Parkinson’s Disease Mice
- Cognitive and motor profiles in biologically defined Parkinson's and Alzheimer's disease