PTSD Psychotherapy Outcome Predicted by Brain Activation During Emotional Reactivity and Regulation

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This study investigates whether baseline brain activation patterns during emotional reactivity and regulation predict outcomes for individuals undergoing prolonged exposure therapy for PTSD. Using fMRI data from participants assigned to either immediate treatment or a waiting list, the authors analyzed how specific neural responses moderated symptom reduction. The findings suggest that greater prefrontal engagement and reduced amygdala activity during initial threat processing are associated with better treatment response.

ID
1202f9e282af46a8
Source org
OpenAlex
Author
Gregory A. Fonzo (VA Palo Alto Health Care System), Madeleine S. Goodkind (VA Palo Alto Health Care System), Desmond J. Oathes (VA Palo Alto Health Care System), Yevgeniya V. Zaiko (VA Palo Alto Health Care System), Meredith Harvey (VA Palo Alto Health Care System), Kathy Peng (VA Palo Alto Health Care System), Michal Weiss (VA Palo Alto Health Care System), Allison L. Thompson (VA Palo Alto Health Care System), Sanno Zack (VA Palo Alto Health Care System), Steven E. Lindley (VA Palo Alto Health Care System), Bruce A. Arnow (VA Palo Alto Health Care System), Booil Jo (VA Palo Alto Health Care System), James J. Gross (VA Palo Alto Health Care System), Barbara O. Rothbaum (VA Palo Alto Health Care System), Amit Etkin (VA Palo Alto Health Care System)
Published
2017-07-18
OA status
bronze
DOI
10.1176/appi.ajp.2017.16091072
PMID
Not recorded
PMCID
Not recorded
Citations
152

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BibTeX

@article{allodium:1202f9e282af46a8,
  title = {PTSD Psychotherapy Outcome Predicted by Brain Activation During Emotional Reactivity and Regulation},
  author = {Gregory A. Fonzo and Madeleine S. Goodkind and Desmond J. Oathes and Yevgeniya V. Zaiko and Meredith Harvey and Kathy Peng and Michal Weiss and Allison L. Thompson and Sanno Zack and Steven E. Lindley and Bruce A. Arnow and Booil Jo and James J. Gross and Barbara O. Rothbaum and Amit Etkin},
  year = {2017},
  journal = {OpenAlex},
  doi = {10.1176/appi.ajp.2017.16091072},
  url = {https://doi.org/10.1176/appi.ajp.2017.16091072}
}

RIS

TY  - JOUR
TI  - PTSD Psychotherapy Outcome Predicted by Brain Activation During Emotional Reactivity and Regulation
AU  - Fonzo, Gregory A.
AU  - Goodkind, Madeleine S.
AU  - Oathes, Desmond J.
AU  - Zaiko, Yevgeniya V.
AU  - Harvey, Meredith
AU  - Peng, Kathy
AU  - Weiss, Michal
AU  - Thompson, Allison L.
AU  - Zack, Sanno
AU  - Lindley, Steven E.
AU  - Arnow, Bruce A.
AU  - Jo, Booil
AU  - Gross, James J.
AU  - Rothbaum, Barbara O.
AU  - Etkin, Amit
PY  - 2017
PB  - OpenAlex
DO  - 10.1176/appi.ajp.2017.16091072
UR  - https://doi.org/10.1176/appi.ajp.2017.16091072
ER  -

APA

Fonzo, G. A., Goodkind, M. S., Oathes, D. J., Zaiko, Y. V., Harvey, M., Peng, K., Weiss, M., Thompson, A. L., Zack, S., Lindley, S. E., Arnow, B. A., Jo, B., Gross, J. J., Rothbaum, B. O., & Etkin, A. (2017). PTSD Psychotherapy Outcome Predicted by Brain Activation During Emotional Reactivity and Regulation. OpenAlex. https://doi.org/10.1176/appi.ajp.2017.16091072

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