Neural predictors of treatment outcome through emotion regulation in internalizing disorders: a narrative review

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This narrative review summarizes functional magnetic resonance imaging studies investigating how neural activity during explicit and implicit emotion regulation predicts treatment outcomes for internalizing disorders. It highlights that baseline prefrontal cortex activity often serves as a predictor, with directionality varying between explicit reappraisal tasks and implicit interference tasks. The resource is intended for researchers or clinicians interested in the neurobiological mechanisms underlying treatment response heterogeneity.

ID
8a2a908c58024b3e
Source org
PubMed Central
Author
Heide Klumpp (Edward Hines, Jr. VA Hospital), Delaney K. Davey (University of Illinois Chicago), Scott A. Langenecker (The Ohio State University)
Published
2026-03-07
OA status
gold
DOI
10.1038/s41398-026-03908-8
PMID
Not recorded
PMCID
Not recorded
Citations
0

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BibTeX

@article{allodium:8a2a908c58024b3e,
  title = {Neural predictors of treatment outcome through emotion regulation in internalizing disorders: a narrative review},
  author = {Heide Klumpp and Delaney K. Davey and Scott A. Langenecker},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1038/s41398-026-03908-8},
  url = {https://doi.org/10.1038/s41398-026-03908-8}
}

RIS

TY  - JOUR
TI  - Neural predictors of treatment outcome through emotion regulation in internalizing disorders: a narrative review
AU  - Klumpp, Heide
AU  - Davey, Delaney K.
AU  - Langenecker, Scott A.
PY  - 2026
PB  - PubMed Central
DO  - 10.1038/s41398-026-03908-8
UR  - https://doi.org/10.1038/s41398-026-03908-8
ER  - 

APA

Klumpp, H., Davey, D. K., & Langenecker, S. A. (2026). Neural predictors of treatment outcome through emotion regulation in internalizing disorders: a narrative review. PubMed Central. https://doi.org/10.1038/s41398-026-03908-8

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