Network changes associated with transdiagnostic depressive symptom improvement following cognitive behavioral therapy in MDD and PTSD

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This study uses graph theory and network science to examine transdiagnostic neural mechanisms underlying depressive symptom improvement after cognitive behavioral therapy in patients with major depressive disorder or PTSD. The research analyzes longitudinal fMRI data from 33 patients and 31 healthy controls to identify changes in brain network connectivity associated with reduced depression severity. Findings suggest that increased segregation of the Ventral Attention system following treatment may facilitate improved cognitive control by reducing emotional attention's influence on cognitive processes.

ID
832d838339044d14
Source org
PubMed Central
Author
Zhen Yang (University of Pennsylvania), Shi Gu (University of Pennsylvania), Nicolas Honnorat (University of Pennsylvania), Kristin A. Linn (University of Pennsylvania), Russell T. Shinohara (University of Pennsylvania), Irem Aselcioglu (University of Pennsylvania), Steven E. Bruce (Washington University in St. Louis), Desmond J. Oathes (University of Pennsylvania), Christos Davatzikos (University of Pennsylvania), Theodore D. Satterthwaite (University of Pennsylvania), Danielle S. Bassett (University of Pennsylvania), Yvette I. Sheline (University of Pennsylvania)
Published
2018-08-13
OA status
hybrid
DOI
10.1038/s41380-018-0201-7
PMID
Not recorded
PMCID
Not recorded
Citations
45

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BibTeX

@article{allodium:832d838339044d14,
  title = {Network changes associated with transdiagnostic depressive symptom improvement following cognitive behavioral therapy in MDD and PTSD},
  author = {Zhen Yang and Shi Gu and Nicolas Honnorat and Kristin A. Linn and Russell T. Shinohara and Irem Aselcioglu and Steven E. Bruce and Desmond J. Oathes and Christos Davatzikos and Theodore D. Satterthwaite and Danielle S. Bassett and Yvette I. Sheline},
  year = {2018},
  journal = {PubMed Central},
  doi = {10.1038/s41380-018-0201-7},
  url = {https://doi.org/10.1038/s41380-018-0201-7}
}

RIS

TY  - JOUR
TI  - Network changes associated with transdiagnostic depressive symptom improvement following cognitive behavioral therapy in MDD and PTSD
AU  - Yang, Zhen
AU  - Gu, Shi
AU  - Honnorat, Nicolas
AU  - Linn, Kristin A.
AU  - Shinohara, Russell T.
AU  - Aselcioglu, Irem
AU  - Bruce, Steven E.
AU  - Oathes, Desmond J.
AU  - Davatzikos, Christos
AU  - Satterthwaite, Theodore D.
AU  - Bassett, Danielle S.
AU  - Sheline, Yvette I.
PY  - 2018
PB  - PubMed Central
DO  - 10.1038/s41380-018-0201-7
UR  - https://doi.org/10.1038/s41380-018-0201-7
ER  - 

APA

Yang, Z., Gu, S., Honnorat, N., Linn, K. A., Shinohara, R. T., Aselcioglu, I., Bruce, S. E., Oathes, D. J., Davatzikos, C., Satterthwaite, T. D., Bassett, D. S., & Sheline, Y. I. (2018). Network changes associated with transdiagnostic depressive symptom improvement following cognitive behavioral therapy in MDD and PTSD. PubMed Central. https://doi.org/10.1038/s41380-018-0201-7

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