Platform trial of smartphone-based cognitive–behavioural therapy (CBT) for depressive symptoms among people with no or subthreshold depression: a protocol for the Best, Efficient and Affordable Training in Resilience in Constant Evolution (BEATRICE) platform trial

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This protocol describes the BEATRICE platform trial, which evaluates smartphone-delivered cognitive-behavioural therapy for adults with no or subthreshold depressive symptoms. The study aims to optimize treatment algorithms by sequentially testing various CBT modules and personalized interventions over 12 months. It is designed for researchers and clinicians interested in digital mental health prevention strategies and adaptive trial methodologies.

ID
125a8c37890e403c
Source org
PubMed Central
Author
Toshi A Furukawa (Kyoto University), Hisashi Noma (The Graduate University for Advanced Studies, SOKENDAI), Masahiro Kojima (Chuo University), Aran Tajika (Kyoto University), R Toyomoto (Kyoto University), Masatsugu Sakata (Nagoya City University), Yan Luo (The University of Tokyo), Kosuke Inoue, (Kyoto University), Masaru Horikoshi (Musashino University), Tatsuo Akechi (Nagoya City University), Norito Kawakami (The University of Tokyo), Naoki Kondo (Kyoto University), Takeo Nakayama (Kyoto University), Shingo Fukuma (Kyoto University), Helen Christensen (Black Dog Institute), Alexis E. Whitton (Black Dog Institute), Wolfgang Lutz (Universität Trier), Pim Cuijpers (Vrije Universiteit Amsterdam), Ronald C Kessler (Harvard University), James Wason (University of Cambridge), Inbal Nahum-Shani (University of Michigan)
Published
2026-03-01
OA status
gold
DOI
10.1136/bmjopen-2025-113603
PMID
Not recorded
PMCID
Not recorded
Citations
0

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BibTeX

@article{allodium:125a8c37890e403c,
  title = {Platform trial of smartphone-based cognitive–behavioural therapy (CBT) for depressive symptoms among people with no or subthreshold depression: a protocol for the Best, Efficient and Affordable Training in Resilience in Constant Evolution (BEATRICE) platform trial},
  author = {Toshi A Furukawa and Hisashi Noma and Masahiro Kojima and Aran Tajika and R Toyomoto and Masatsugu Sakata and Yan Luo and Kosuke Inoue, and Masaru Horikoshi and Tatsuo Akechi and Norito Kawakami and Naoki Kondo and Takeo Nakayama and Shingo Fukuma and Helen Christensen and Alexis E. Whitton and Wolfgang Lutz and Pim Cuijpers and Ronald C Kessler and James Wason and Inbal Nahum-Shani},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1136/bmjopen-2025-113603},
  url = {https://doi.org/10.1136/bmjopen-2025-113603}
}

RIS

TY  - JOUR
TI  - Platform trial of smartphone-based cognitive–behavioural therapy (CBT) for depressive symptoms among people with no or subthreshold depression: a protocol for the Best, Efficient and Affordable Training in Resilience in Constant Evolution (BEATRICE) platform trial
AU  - Furukawa, Toshi A
AU  - Noma, Hisashi
AU  - Kojima, Masahiro
AU  - Tajika, Aran
AU  - Toyomoto, R
AU  - Sakata, Masatsugu
AU  - Luo, Yan
AU  - Inoue,, Kosuke
AU  - Horikoshi, Masaru
AU  - Akechi, Tatsuo
AU  - Kawakami, Norito
AU  - Kondo, Naoki
AU  - Nakayama, Takeo
AU  - Fukuma, Shingo
AU  - Christensen, Helen
AU  - Whitton, Alexis E.
AU  - Lutz, Wolfgang
AU  - Cuijpers, Pim
AU  - Kessler, Ronald C
AU  - Wason, James
AU  - Nahum-Shani, Inbal
PY  - 2026
PB  - PubMed Central
DO  - 10.1136/bmjopen-2025-113603
UR  - https://doi.org/10.1136/bmjopen-2025-113603
ER  -

APA

Furukawa, T. A., Noma, H., Kojima, M., Tajika, A., Toyomoto, R., Sakata, M., Luo, Y., Inoue,, K., Horikoshi, M., Akechi, T., Kawakami, N., Kondo, N., Nakayama, T., Fukuma, S., Christensen, H., Whitton, A. E., Lutz, W., Cuijpers, P., Kessler, R. C., Wason, J., & Nahum-Shani, I. (2026). Platform trial of smartphone-based cognitive–behavioural therapy (CBT) for depressive symptoms among people with no or subthreshold depression: a protocol for the Best, Efficient and Affordable Training in Resilience in Constant Evolution (BEATRICE) platform trial. PubMed Central. https://doi.org/10.1136/bmjopen-2025-113603

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