Understanding betel nut addiction: a review of harmful consequences, underlying neurobiology, and emerging intervention strategies

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This review examines betel nut addiction, covering its epidemiology, health risks such as oral cancer, and neurobiological mechanisms involving arecoline. It outlines potential intervention strategies including pharmacological treatments, neuromodulation, cognitive-behavioral therapy, and public health policies. The resource is intended for readers interested in the scientific understanding and management of this psychoactive substance use disorder.

ID
4f203db4f7d74c24
Source org
PubMed Central
Author
Mengying Shao (Hunan University of Traditional Chinese Medicine), Lizhen Zhuang (Hunan University of Traditional Chinese Medicine), Saifei Xie (Hunan University of Traditional Chinese Medicine), Taohua Pan (Hunan University of Traditional Chinese Medicine), Yan Xie (Hunan University of Traditional Chinese Medicine), Shuhang Fan (Hunan University of Traditional Chinese Medicine), Jincai Guo (Hunan University of Traditional Chinese Medicine), Hui Xie (Hunan University of Traditional Chinese Medicine)
Published
2026-02-09
OA status
gold
DOI
10.1038/s41398-026-03875-0
PMID
Not recorded
PMCID
Not recorded
Citations
3

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BibTeX

@article{allodium:4f203db4f7d74c24,
  title = {Understanding betel nut addiction: a review of harmful consequences, underlying neurobiology, and emerging intervention strategies},
  author = {Mengying Shao and Lizhen Zhuang and Saifei Xie and Taohua Pan and Yan Xie and Shuhang Fan and Jincai Guo and Hui Xie},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1038/s41398-026-03875-0},
  url = {https://doi.org/10.1038/s41398-026-03875-0}
}

RIS

TY  - JOUR
TI  - Understanding betel nut addiction: a review of harmful consequences, underlying neurobiology, and emerging intervention strategies
AU  - Shao, Mengying
AU  - Zhuang, Lizhen
AU  - Xie, Saifei
AU  - Pan, Taohua
AU  - Xie, Yan
AU  - Fan, Shuhang
AU  - Guo, Jincai
AU  - Xie, Hui
PY  - 2026
PB  - PubMed Central
DO  - 10.1038/s41398-026-03875-0
UR  - https://doi.org/10.1038/s41398-026-03875-0
ER  -

APA

Shao, M., Zhuang, L., Xie, S., Pan, T., Xie, Y., Fan, S., Guo, J., & Xie, H. (2026). Understanding betel nut addiction: a review of harmful consequences, underlying neurobiology, and emerging intervention strategies. PubMed Central. https://doi.org/10.1038/s41398-026-03875-0

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