Clinical features and genetic mechanisms of anxiety, fear, and avoidance: A comprehensive review of five anxiety disorders
Overview
This narrative review examines the clinical features, neurobiological mechanisms, and genetic underpinnings of five anxiety disorders, categorizing them into fear-dominant, mixed, and anxiety-dominant groups. The authors synthesize findings from neuropsychological, brain function, and genetic studies to highlight shared risk factors and distinct treatment responses across these categories. The resource is intended for readers interested in the intersection of clinical presentation and biological mechanisms in anxiety disorders.
- ID
55831198f49e48b0- Source org
- PubMed Central
- Author
- Kazutaka Ohi (Gifu University), Daisuke Fujikane (Gifu University), Kentaro Takai (Gifu University), Ayumi Kuramitsu (Gifu University), Yukimasa Muto (Gifu University), Shunsuke Sugiyama (Gifu University), Toshiki Shioiri (Gifu University)
- Published
- 2025-08-19
- OA status
- hybrid
- DOI
- 10.1038/s41380-025-03155-1
- PMID
- Not recorded
- PMCID
- Not recorded
- Citations
- 16
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Cite this entry
BibTeX
@article{allodium:55831198f49e48b0,
title = {Clinical features and genetic mechanisms of anxiety, fear, and avoidance: A comprehensive review of five anxiety disorders},
author = {Kazutaka Ohi and Daisuke Fujikane and Kentaro Takai and Ayumi Kuramitsu and Yukimasa Muto and Shunsuke Sugiyama and Toshiki Shioiri},
year = {2025},
journal = {PubMed Central},
doi = {10.1038/s41380-025-03155-1},
url = {https://doi.org/10.1038/s41380-025-03155-1}
}RIS
TY - JOUR TI - Clinical features and genetic mechanisms of anxiety, fear, and avoidance: A comprehensive review of five anxiety disorders AU - Ohi, Kazutaka AU - Fujikane, Daisuke AU - Takai, Kentaro AU - Kuramitsu, Ayumi AU - Muto, Yukimasa AU - Sugiyama, Shunsuke AU - Shioiri, Toshiki PY - 2025 PB - PubMed Central DO - 10.1038/s41380-025-03155-1 UR - https://doi.org/10.1038/s41380-025-03155-1 ER -
APA
Ohi, K., Fujikane, D., Takai, K., Kuramitsu, A., Muto, Y., Sugiyama, S., & Shioiri, T. (2025). Clinical features and genetic mechanisms of anxiety, fear, and avoidance: A comprehensive review of five anxiety disorders. PubMed Central. https://doi.org/10.1038/s41380-025-03155-1
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