Effect of D-Cycloserine on the Effect of Concentrated Exposure and Response Prevention in Difficult-to-Treat Obsessive-Compulsive Disorder

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This randomized controlled trial investigates whether D-cycloserine enhances the effects of concentrated exposure and response prevention in adults with difficult-to-treat obsessive-compulsive disorder. The study compares outcomes among patients receiving 100 mg or 250 mg of D-cycloserine versus a placebo alongside the treatment protocol. It reports on symptom changes, diagnostic status, and secondary measures such as anxiety and quality of life over a 12-month follow-up period.

ID
72aa5f7fb6e545ea
Source org
OpenAlex
Author
Gerd Kvale (Haukeland University Hospital), Bjarne Hansen (Haukeland University Hospital), Kristen Hagen (Haukeland University Hospital), Jonathan S. Abramowitz (University of North Carolina at Chapel Hill), Tore Børtveit (Haukeland University Hospital), Michelle G. Craske (University of California, Los Angeles), Martin E. Franklin (Memorial Hospital), Svein Haseth (St Olav's University Hospital), Joseph A. Himle (University of Michigan), Sigurd W. Hystad (University of Bergen), Unn Beate Kristensen (Oslo University Hospital), Gunvor Launes (Sørlandet Sykehus), Anders Lund (Haukeland University Hospital), Stian Solem (Norwegian University of Science and Technology), Lars‐Göran Öst (Stockholm University)
Published
2020-08-13
OA status
gold
DOI
10.1001/jamanetworkopen.2020.13249
PMID
Not recorded
PMCID
Not recorded
Citations
36

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BibTeX

@article{allodium:72aa5f7fb6e545ea,
  title = {Effect of D-Cycloserine on the Effect of Concentrated Exposure and Response Prevention in Difficult-to-Treat Obsessive-Compulsive Disorder},
  author = {Gerd Kvale and Bjarne Hansen and Kristen Hagen and Jonathan S. Abramowitz and Tore Børtveit and Michelle G. Craske and Martin E. Franklin and Svein Haseth and Joseph A. Himle and Sigurd W. Hystad and Unn Beate Kristensen and Gunvor Launes and Anders Lund and Stian Solem and Lars‐Göran Öst},
  year = {2020},
  journal = {OpenAlex},
  doi = {10.1001/jamanetworkopen.2020.13249},
  url = {https://doi.org/10.1001/jamanetworkopen.2020.13249}
}

RIS

TY  - JOUR
TI  - Effect of D-Cycloserine on the Effect of Concentrated Exposure and Response Prevention in Difficult-to-Treat Obsessive-Compulsive Disorder
AU  - Kvale, Gerd
AU  - Hansen, Bjarne
AU  - Hagen, Kristen
AU  - Abramowitz, Jonathan S.
AU  - Børtveit, Tore
AU  - Craske, Michelle G.
AU  - Franklin, Martin E.
AU  - Haseth, Svein
AU  - Himle, Joseph A.
AU  - Hystad, Sigurd W.
AU  - Kristensen, Unn Beate
AU  - Launes, Gunvor
AU  - Lund, Anders
AU  - Solem, Stian
AU  - Öst, Lars‐Göran
PY  - 2020
PB  - OpenAlex
DO  - 10.1001/jamanetworkopen.2020.13249
UR  - https://doi.org/10.1001/jamanetworkopen.2020.13249
ER  -

APA

Kvale, G., Hansen, B., Hagen, K., Abramowitz, J. S., Børtveit, T., Craske, M. G., Franklin, M. E., Haseth, S., Himle, J. A., Hystad, S. W., Kristensen, U. B., Launes, G., Lund, A., Solem, S., & Öst, L. (2020). Effect of D-Cycloserine on the Effect of Concentrated Exposure and Response Prevention in Difficult-to-Treat Obsessive-Compulsive Disorder. OpenAlex. https://doi.org/10.1001/jamanetworkopen.2020.13249

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