Model-based economic evaluation of non-pharmacological interventions for fatigue in patients with long-term medical conditions in the UK

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This study uses decision analytic modeling to evaluate the cost-effectiveness of non-pharmacological fatigue interventions for patients with long-term medical conditions within the UK NHS context. It compares individual and group formats of physical activity promotion, CBT-Fatigue, and mindfulness against usual care, measuring outcomes in quality-adjusted life years (QALYs) and net monetary benefit. The analysis suggests that group interventions generally offer greater value than individual ones, though uncertainty remains regarding the most cost-effective option due to limitations in the underlying evidence base.

ID
782e025259f9483b
Source org
PubMed Central
Author
Mon Mon-Yee (University of Sheffield), Christopher Burton (University of Sheffield), Joanna Leaviss (University of Sheffield), Jessica E. Forsyth (University of Sheffield), George Daly (University of Sheffield), S Christina Davis (University of Sheffield)
Published
2026-04-01
OA status
gold
DOI
10.1136/bmjopen-2025-102846
PMID
Not recorded
PMCID
Not recorded
Citations
1

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BibTeX

@article{allodium:782e025259f9483b,
  title = {Model-based economic evaluation of non-pharmacological interventions for fatigue in patients with long-term medical conditions in the UK},
  author = {Mon Mon-Yee and Christopher Burton and Joanna Leaviss and Jessica E. Forsyth and George Daly and S Christina Davis},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1136/bmjopen-2025-102846},
  url = {https://doi.org/10.1136/bmjopen-2025-102846}
}

RIS

TY  - JOUR
TI  - Model-based economic evaluation of non-pharmacological interventions for fatigue in patients with long-term medical conditions in the UK
AU  - Mon-Yee, Mon
AU  - Burton, Christopher
AU  - Leaviss, Joanna
AU  - Forsyth, Jessica E.
AU  - Daly, George
AU  - Davis, S Christina
PY  - 2026
PB  - PubMed Central
DO  - 10.1136/bmjopen-2025-102846
UR  - https://doi.org/10.1136/bmjopen-2025-102846
ER  -

APA

Mon-Yee, M., Burton, C., Leaviss, J., Forsyth, J. E., Daly, G., & Davis, S. C. (2026). Model-based economic evaluation of non-pharmacological interventions for fatigue in patients with long-term medical conditions in the UK. PubMed Central. https://doi.org/10.1136/bmjopen-2025-102846

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