Efficacy of Cognitive Behavioral Therapy and Physical Exercise in Alleviating Treatment-Induced Menopausal Symptoms in Patients With Breast Cancer: Results of a Randomized, Controlled, Multicenter Trial

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This randomized controlled trial evaluates the impact of cognitive behavioral therapy, physical exercise, and their combination on menopausal symptoms in 422 breast cancer patients with treatment-induced menopause. The study compares these interventions against a waiting list control group using self-report measures at baseline, 12 weeks, and six months. Results indicate that all intervention groups experienced significant reductions in endocrine and urinary symptoms compared to the control group. Additionally, groups receiving CBT showed improvements in perceived hot flash burden and sexual activity.

ID
7d04a796871644aa
Source org
OpenAlex
Author
Saskia F. A. Duijts (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Marc van Beurden (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Hester S. A. Oldenburg (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Myra S. Hunter (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Jacobien M. Kieffer (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Martijn M. Stuiver (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Miranda A. Gerritsma (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Marian B. E. Menke‐Pluymers (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Peter W. Plaisier (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Herman Rijna (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), A.M.F. Lopes Cardozo (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Gert-Jan Timmers (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Suzan van der Meij (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Henk van Veen (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Nina Bijker (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Louise M. de Widt-Levert (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Maud M. Geenen (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Gijsbert Heuff (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Eric J. van Dulken (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Epie Boven (Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital), Neil K. Aaronson (The Netherlands Cancer Institute)
Published
2012-10-09
OA status
bronze
DOI
10.1200/jco.2012.41.8525
PMID
Not recorded
PMCID
Not recorded
Citations
222

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BibTeX

@article{allodium:7d04a796871644aa,
  title = {Efficacy of Cognitive Behavioral Therapy and Physical Exercise in Alleviating Treatment-Induced Menopausal Symptoms in Patients With Breast Cancer: Results of a Randomized, Controlled, Multicenter Trial},
  author = {Saskia F. A. Duijts and Marc van Beurden and Hester S. A. Oldenburg and Myra S. Hunter and Jacobien M. Kieffer and Martijn M. Stuiver and Miranda A. Gerritsma and Marian B. E. Menke‐Pluymers and Peter W. Plaisier and Herman Rijna and A.M.F. Lopes Cardozo and Gert-Jan Timmers and Suzan van der Meij and Henk van Veen and Nina Bijker and Louise M. de Widt-Levert and Maud M. Geenen and Gijsbert Heuff and Eric J. van Dulken and Epie Boven and Neil K. Aaronson},
  year = {2012},
  journal = {OpenAlex},
  doi = {10.1200/jco.2012.41.8525},
  url = {https://doi.org/10.1200/jco.2012.41.8525}
}

RIS

TY  - JOUR
TI  - Efficacy of Cognitive Behavioral Therapy and Physical Exercise in Alleviating Treatment-Induced Menopausal Symptoms in Patients With Breast Cancer: Results of a Randomized, Controlled, Multicenter Trial
AU  - Duijts, Saskia F. A.
AU  - Beurden, Marc van
AU  - Oldenburg, Hester S. A.
AU  - Hunter, Myra S.
AU  - Kieffer, Jacobien M.
AU  - Stuiver, Martijn M.
AU  - Gerritsma, Miranda A.
AU  - Menke‐Pluymers, Marian B. E.
AU  - Plaisier, Peter W.
AU  - Rijna, Herman
AU  - Cardozo, A.M.F. Lopes
AU  - Timmers, Gert-Jan
AU  - Meij, Suzan van der
AU  - Veen, Henk van
AU  - Bijker, Nina
AU  - Widt-Levert, Louise M. de
AU  - Geenen, Maud M.
AU  - Heuff, Gijsbert
AU  - Dulken, Eric J. van
AU  - Boven, Epie
AU  - Aaronson, Neil K.
PY  - 2012
PB  - OpenAlex
DO  - 10.1200/jco.2012.41.8525
UR  - https://doi.org/10.1200/jco.2012.41.8525
ER  -

APA

Duijts, S. F. A., Beurden, M. V., Oldenburg, H. S. A., Hunter, M. S., Kieffer, J. M., Stuiver, M. M., Gerritsma, M. A., Menke‐Pluymers, M. B. E., Plaisier, P. W., Rijna, H., Cardozo, A. L., Timmers, G., Meij, S. V. D., Veen, H. V., Bijker, N., Widt-Levert, L. M. D., Geenen, M. M., Heuff, G., Dulken, E. J. V., Boven, E., & Aaronson, N. K. (2012). Efficacy of Cognitive Behavioral Therapy and Physical Exercise in Alleviating Treatment-Induced Menopausal Symptoms in Patients With Breast Cancer: Results of a Randomized, Controlled, Multicenter Trial. OpenAlex. https://doi.org/10.1200/jco.2012.41.8525

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