Individual Participant Data Meta‐Analysis Identifies Risk Factors for Acute and Persistent Posttraumatic Stress Disorder and Depression Symptoms Following Trauma

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This study presents an individual participant data meta-analysis pooling data from five prospective studies to identify risk factors for acute and persistent posttraumatic stress disorder (PTSD) and major depressive disorder (MDD). The authors examined associations between demographic variables, trauma type, and symptom severity across acute and follow-up periods. Findings indicate that female sex is associated with increased risk for both conditions, while accident-related trauma is linked to reduced risk compared to assault. Additionally, the analysis suggests that early MDD symptoms and PTSD reexperiencing are associated with the persistence of psychopathology.

ID
813726160860467e
Source org
PubMed Central
Author
Andrew Ratanatharathorn (Harvard University), Richard A. Bryant (Black Dog Institute), Ronald C. Kessler (Harvard University), Katherine M. Keyes (Columbia University), Yutaka Matsuoka (National Cancer Research Institute), Miranda Olff (Arq Psychotrauma Expert Group), Renato Polimanti (Yale University), Andrew Rundle (Columbia University), Karestan C. Koenen (Broad Institute), Arieh Y. Shalev (Hebrew University of Jerusalem)
Published
2026-01-01
OA status
hybrid
DOI
10.1155/da/9859948
PMID
Not recorded
PMCID
Not recorded
Citations
0

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BibTeX

@article{allodium:813726160860467e,
  title = {Individual Participant Data Meta‐Analysis Identifies Risk Factors for Acute and Persistent Posttraumatic Stress Disorder and Depression Symptoms Following Trauma},
  author = {Andrew Ratanatharathorn and Richard A. Bryant and Ronald C. Kessler and Katherine M. Keyes and Yutaka Matsuoka and Miranda Olff and Renato Polimanti and Andrew Rundle and Karestan C. Koenen and Arieh Y. Shalev},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1155/da/9859948},
  url = {https://doi.org/10.1155/da/9859948}
}

RIS

TY  - JOUR
TI  - Individual Participant Data Meta‐Analysis Identifies Risk Factors for Acute and Persistent Posttraumatic Stress Disorder and Depression Symptoms Following Trauma
AU  - Ratanatharathorn, Andrew
AU  - Bryant, Richard A.
AU  - Kessler, Ronald C.
AU  - Keyes, Katherine M.
AU  - Matsuoka, Yutaka
AU  - Olff, Miranda
AU  - Polimanti, Renato
AU  - Rundle, Andrew
AU  - Koenen, Karestan C.
AU  - Shalev, Arieh Y.
PY  - 2026
PB  - PubMed Central
DO  - 10.1155/da/9859948
UR  - https://doi.org/10.1155/da/9859948
ER  - 

APA

Ratanatharathorn, A., Bryant, R. A., Kessler, R. C., Keyes, K. M., Matsuoka, Y., Olff, M., Polimanti, R., Rundle, A., Koenen, K. C., & Shalev, A. Y. (2026). Individual Participant Data Meta‐Analysis Identifies Risk Factors for Acute and Persistent Posttraumatic Stress Disorder and Depression Symptoms Following Trauma. PubMed Central. https://doi.org/10.1155/da/9859948

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