Identifying what works in mental health apps through meta-regression analyses of 169 trials

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This meta-analysis examines the association between specific cognitive behavioral elements in 169 mental health app trials and improvements in depression and anxiety. The study identifies desensitization, stimulus control, and activity scheduling as robustly linked to depression improvement, while exposure-based elements correlate with anxiety reduction. It also notes that interventions incorporating a greater number of active elements tend to be more effective.

ID
a265a564c40b448e
Source org
PubMed Central
Author
Jannis T. Kraiss (University of Twente), Felix Fiß (University of Twente), Farid Chakhssi (Dimence), Fatma Betül Aktas (Ibn Haldun University), Jurrijn Alexander Koelen (University of Twente), Jorge Piano Simões (University of Twente)
Published
2026-03-11
OA status
gold
DOI
10.1038/s41746-026-02466-z
PMID
Not recorded
PMCID
Not recorded
Citations
0

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BibTeX

@article{allodium:a265a564c40b448e,
  title = {Identifying what works in mental health apps through meta-regression analyses of 169 trials},
  author = {Jannis T. Kraiss and Felix Fiß and Farid Chakhssi and Fatma Betül Aktas and Jurrijn Alexander Koelen and Jorge Piano Simões},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1038/s41746-026-02466-z},
  url = {https://doi.org/10.1038/s41746-026-02466-z}
}

RIS

TY  - JOUR
TI  - Identifying what works in mental health apps through meta-regression analyses of 169 trials
AU  - Kraiss, Jannis T.
AU  - Fiß, Felix
AU  - Chakhssi, Farid
AU  - Aktas, Fatma Betül
AU  - Koelen, Jurrijn Alexander
AU  - Simões, Jorge Piano
PY  - 2026
PB  - PubMed Central
DO  - 10.1038/s41746-026-02466-z
UR  - https://doi.org/10.1038/s41746-026-02466-z
ER  -

APA

Kraiss, J. T., Fiß, F., Chakhssi, F., Aktas, F. B., Koelen, J. A., & Simões, J. P. (2026). Identifying what works in mental health apps through meta-regression analyses of 169 trials. PubMed Central. https://doi.org/10.1038/s41746-026-02466-z

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