Effect of internet-delivered exposure therapy versus healthy lifestyle promotion for patients with persistent physical symptoms (SOMEX1): a randomized controlled trial with planned moderator analysis

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This randomized controlled trial compares internet-delivered exposure therapy against healthy lifestyle promotion for primary care patients with persistent physical symptoms. The study reports that while exposure therapy did not significantly reduce overall somatic symptom burden compared to the control, it was superior in reducing symptom preoccupation. Results suggest that patients with higher baseline symptom burden or preoccupation may derive greater benefit from the intervention.

ID
b813d7a87bb14809
Source org
PubMed Central
Author
Jonna Hybelius (Karolinska Institutet), Sandra af Winklerfelt Hammarberg (Karolinska Institutet), Sigrid Salomonsson (Karolinska Institutet), Caroline Wachtler (Karolinska Institutet), Majken Epstein (Karolinska Institutet), Anna Olsson (Stockholm Health Care Services), Eva K. Strand (Stockholm Health Care Services), L. De Winter (Stockholm Health Care Services), Tomas Åkerlund (Stockholm Health Care Services), Daniel Björkander (Stockholm Health Care Services), Amanda Kosic (Örebro University), Gabriel Chahin (Stockholm Health Care Services), John Wallert (Karolinska Institutet), Eva Toth-Pal (Karolinska Institutet), Steven Nordin (Umeå University), Erland Axelsson (Karolinska Institutet)
Published
2025-01-01
OA status
hybrid
DOI
10.1017/S0033291725101244
PMID
Not recorded
PMCID
Not recorded
Citations
2

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BibTeX

@article{allodium:b813d7a87bb14809,
  title = {Effect of internet-delivered exposure therapy versus healthy lifestyle promotion for patients with persistent physical symptoms (SOMEX1): a randomized controlled trial with planned moderator analysis},
  author = {Jonna Hybelius and Sandra af Winklerfelt Hammarberg and Sigrid Salomonsson and Caroline Wachtler and Majken Epstein and Anna Olsson and Eva K. Strand and L. De Winter and Tomas Åkerlund and Daniel Björkander and Amanda Kosic and Gabriel Chahin and John Wallert and Eva Toth-Pal and Steven Nordin and Erland Axelsson},
  year = {2025},
  journal = {PubMed Central},
  doi = {10.1017/S0033291725101244},
  url = {https://doi.org/10.1017/S0033291725101244}
}

RIS

TY  - JOUR
TI  - Effect of internet-delivered exposure therapy versus healthy lifestyle promotion for patients with persistent physical symptoms (SOMEX1): a randomized controlled trial with planned moderator analysis
AU  - Hybelius, Jonna
AU  - Hammarberg, Sandra af Winklerfelt
AU  - Salomonsson, Sigrid
AU  - Wachtler, Caroline
AU  - Epstein, Majken
AU  - Olsson, Anna
AU  - Strand, Eva K.
AU  - Winter, L. De
AU  - Åkerlund, Tomas
AU  - Björkander, Daniel
AU  - Kosic, Amanda
AU  - Chahin, Gabriel
AU  - Wallert, John
AU  - Toth-Pal, Eva
AU  - Nordin, Steven
AU  - Axelsson, Erland
PY  - 2025
PB  - PubMed Central
DO  - 10.1017/S0033291725101244
UR  - https://doi.org/10.1017/S0033291725101244
ER  -

APA

Hybelius, J., Hammarberg, S. A. W., Salomonsson, S., Wachtler, C., Epstein, M., Olsson, A., Strand, E. K., Winter, L. D., Åkerlund, T., Björkander, D., Kosic, A., Chahin, G., Wallert, J., Toth-Pal, E., Nordin, S., & Axelsson, E. (2025). Effect of internet-delivered exposure therapy versus healthy lifestyle promotion for patients with persistent physical symptoms (SOMEX1): a randomized controlled trial with planned moderator analysis. PubMed Central. https://doi.org/10.1017/S0033291725101244

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