Refractory depression – mechanisms and efficacy of radically open dialectical behaviour therapy (RefraMED): findings of a randomised trial on benefits and harms

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This paper reports on a randomized trial evaluating Radically Open Dialectical Behaviour Therapy (RO DBT) for refractory depression compared to treatment as usual alone. The study found that RO DBT significantly reduced depressive symptoms immediately after the 7-month intervention period, but this difference was not statistically significant at the 12- and 18-month follow-ups. Participants in the therapy group also reported better psychological flexibility and emotional coping, though they experienced more serious adverse reactions than the control group.

ID
c0d3059062d444d5
Source org
OpenAlex
Author
Thomas R. Lynch (University of Southampton), Roelie Hempel (University of Southampton), Ben Whalley (University of Plymouth), Sarah Byford (King's College London), Rampaul Chamba, Paul B. S. Clarke (University of Essex), Susan Clarke (Dorset HealthCare University NHS Foundation Trust), David Kingdon (University of Southampton), Heather O’Mahen (University of Exeter), Bob Remington (University of Southampton), Sophie Rushbrook (Dorset HealthCare University NHS Foundation Trust), James Shearer (King's College London), Maggie Stanton (Southern Health NHS Foundation Trust), Michaela Swales (Bangor University), Alan Watkins (Swansea University), Ian Russell (Swansea University)
Published
2019-07-18
OA status
hybrid
DOI
10.1192/bjp.2019.53
PMID
Not recorded
PMCID
Not recorded
Citations
34

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BibTeX

@article{allodium:c0d3059062d444d5,
  title = {Refractory depression – mechanisms and efficacy of radically open dialectical behaviour therapy (RefraMED): findings of a randomised trial on benefits and harms},
  author = {Thomas R. Lynch and Roelie Hempel and Ben Whalley and Sarah Byford and Rampaul Chamba and Paul B. S. Clarke and Susan Clarke and David Kingdon and Heather O’Mahen and Bob Remington and Sophie Rushbrook and James Shearer and Maggie Stanton and Michaela Swales and Alan Watkins and Ian Russell},
  year = {2019},
  journal = {OpenAlex},
  doi = {10.1192/bjp.2019.53},
  url = {https://doi.org/10.1192/bjp.2019.53}
}

RIS

TY  - JOUR
TI  - Refractory depression – mechanisms and efficacy of radically open dialectical behaviour therapy (RefraMED): findings of a randomised trial on benefits and harms
AU  - Lynch, Thomas R.
AU  - Hempel, Roelie
AU  - Whalley, Ben
AU  - Byford, Sarah
AU  - Chamba, Rampaul
AU  - Clarke, Paul B. S.
AU  - Clarke, Susan
AU  - Kingdon, David
AU  - O’Mahen, Heather
AU  - Remington, Bob
AU  - Rushbrook, Sophie
AU  - Shearer, James
AU  - Stanton, Maggie
AU  - Swales, Michaela
AU  - Watkins, Alan
AU  - Russell, Ian
PY  - 2019
PB  - OpenAlex
DO  - 10.1192/bjp.2019.53
UR  - https://doi.org/10.1192/bjp.2019.53
ER  -

APA

Lynch, T. R., Hempel, R., Whalley, B., Byford, S., Chamba, R., Clarke, P. B. S., Clarke, S., Kingdon, D., O’Mahen, H., Remington, B., Rushbrook, S., Shearer, J., Stanton, M., Swales, M., Watkins, A., & Russell, I. (2019). Refractory depression – mechanisms and efficacy of radically open dialectical behaviour therapy (RefraMED): findings of a randomised trial on benefits and harms. OpenAlex. https://doi.org/10.1192/bjp.2019.53

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