Early Support after Exposure to Trauma (EASE): protocol for a hybrid effectiveness-implementation trial of an internet-based intervention for PTSD prevention

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This paper outlines the protocol for the EASE study, a hybrid effectiveness-implementation trial evaluating Condensed Internet-delivered Prolonged Exposure (CIPE) as an indicated secondary prevention for PTSD. The research targets individuals receiving support from Norwegian municipal crisis teams within seven weeks of a traumatic event and compares CIPE plus treatment as usual against treatment as usual alone. It assesses primary outcomes related to PTSD symptoms at six weeks post-randomization, alongside secondary measures such as depression, insomnia, quality of life, and cost-effectiveness.

ID
ca7be7f242f448da
Source org
PubMed Central
Author
Espen Rasmussen Lassen (University of Oslo), Marianne Skogbrott Birkeland (Norwegian Centre for Violence and Traumatic Stress Studies), Karina M. Egeland (Norwegian Centre for Violence and Traumatic Stress Studies), Lise Eilin Stene (Norwegian Centre for Violence and Traumatic Stress Studies), Dorte Brodersen (Norwegian Centre for Violence and Traumatic Stress Studies), Belinda Ekornås (Norwegian Centre for Violence and Traumatic Stress Studies), Nils Petter Reinholdt (Norwegian Centre for Violence and Traumatic Stress Studies), Egil Kjerstad (NORCE Research AS), Admassu N. Lamu (NORCE Research AS), Gregory A. Aarons (American Academy of Child and Adolescent Psychiatry), Erika L. Crable (University of California, Los Angeles), Maria Bragesjö (Karolinska Institutet), Harald Bækkelund (Norwegian Centre for Violence and Traumatic Stress Studies)
Published
2026-02-05
OA status
gold
DOI
10.1186/s13063-026-09502-z
PMID
Not recorded
PMCID
Not recorded
Citations
0

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BibTeX

@article{allodium:ca7be7f242f448da,
  title = {Early Support after Exposure to Trauma (EASE): protocol for a hybrid effectiveness-implementation trial of an internet-based intervention for PTSD prevention},
  author = {Espen Rasmussen Lassen and Marianne Skogbrott Birkeland and Karina M. Egeland and Lise Eilin Stene and Dorte Brodersen and Belinda Ekornås and Nils Petter Reinholdt and Egil Kjerstad and Admassu N. Lamu and Gregory A. Aarons and Erika L. Crable and Maria Bragesjö and Harald Bækkelund},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1186/s13063-026-09502-z},
  url = {https://doi.org/10.1186/s13063-026-09502-z}
}

RIS

TY  - JOUR
TI  - Early Support after Exposure to Trauma (EASE): protocol for a hybrid effectiveness-implementation trial of an internet-based intervention for PTSD prevention
AU  - Lassen, Espen Rasmussen
AU  - Birkeland, Marianne Skogbrott
AU  - Egeland, Karina M.
AU  - Stene, Lise Eilin
AU  - Brodersen, Dorte
AU  - Ekornås, Belinda
AU  - Reinholdt, Nils Petter
AU  - Kjerstad, Egil
AU  - Lamu, Admassu N.
AU  - Aarons, Gregory A.
AU  - Crable, Erika L.
AU  - Bragesjö, Maria
AU  - Bækkelund, Harald
PY  - 2026
PB  - PubMed Central
DO  - 10.1186/s13063-026-09502-z
UR  - https://doi.org/10.1186/s13063-026-09502-z
ER  -

APA

Lassen, E. R., Birkeland, M. S., Egeland, K. M., Stene, L. E., Brodersen, D., Ekornås, B., Reinholdt, N. P., Kjerstad, E., Lamu, A. N., Aarons, G. A., Crable, E. L., Bragesjö, M., & Bækkelund, H. (2026). Early Support after Exposure to Trauma (EASE): protocol for a hybrid effectiveness-implementation trial of an internet-based intervention for PTSD prevention. PubMed Central. https://doi.org/10.1186/s13063-026-09502-z

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