Response to psychotherapy in borderline personality disorder and methylation status of the BDNF gene

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This study examines the relationship between BDNF gene methylation, childhood trauma, and treatment outcomes in 115 individuals with borderline personality disorder undergoing intensive dialectical behavior therapy. The authors report that responders to therapy showed decreased methylation levels, which were associated with improvements in depression, hopelessness, and impulsivity scores. The resource is intended for researchers or clinicians interested in the biological mechanisms underlying psychotherapy response.

ID
dafb506f3c7f4aae
Source org
OpenAlex
Author
Nader Perroud (University of Geneva), Annick Salzmann (University of Geneva), Paco Prada (University Hospital of Geneva), Rosetta Nicastro (University Hospital of Geneva), M-E Hoeppli (University Hospital of Geneva), Summer Furrer (University Hospital of Geneva), Stefano Ardu (University of Geneva), Ivo Krejci (University of Geneva), Félicien Karege (University Hospital of Geneva), Alain Malafosse (University of Geneva)
Published
2013-01-15
OA status
gold
DOI
10.1038/tp.2012.140
PMID
Not recorded
PMCID
Not recorded
Citations
319

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BibTeX

@article{allodium:dafb506f3c7f4aae,
  title = {Response to psychotherapy in borderline personality disorder and methylation status of the BDNF gene},
  author = {Nader Perroud and Annick Salzmann and Paco Prada and Rosetta Nicastro and M-E Hoeppli and Summer Furrer and Stefano Ardu and Ivo Krejci and Félicien Karege and Alain Malafosse},
  year = {2013},
  journal = {OpenAlex},
  doi = {10.1038/tp.2012.140},
  url = {https://doi.org/10.1038/tp.2012.140}
}

RIS

TY  - JOUR
TI  - Response to psychotherapy in borderline personality disorder and methylation status of the BDNF gene
AU  - Perroud, Nader
AU  - Salzmann, Annick
AU  - Prada, Paco
AU  - Nicastro, Rosetta
AU  - Hoeppli, M-E
AU  - Furrer, Summer
AU  - Ardu, Stefano
AU  - Krejci, Ivo
AU  - Karege, Félicien
AU  - Malafosse, Alain
PY  - 2013
PB  - OpenAlex
DO  - 10.1038/tp.2012.140
UR  - https://doi.org/10.1038/tp.2012.140
ER  -

APA

Perroud, N., Salzmann, A., Prada, P., Nicastro, R., Hoeppli, M., Furrer, S., Ardu, S., Krejci, I., Karege, F., & Malafosse, A. (2013). Response to psychotherapy in borderline personality disorder and methylation status of the BDNF gene. OpenAlex. https://doi.org/10.1038/tp.2012.140

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