Randomized controlled trial on feedback-informed internet-delivered psychodynamic therapy for adolescents with depression: A trial that failed to recruit enough participants

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This paper reports on a randomized controlled trial that was discontinued due to insufficient recruitment of adolescents with depression. The study aimed to evaluate an adaptive, feedback-informed internet-delivered psychodynamic therapy using a predictive algorithm to identify non-responders. Although the trial failed to reach its target sample size of 240 participants, it notes significant within-group improvements in depressive symptoms and anxiety among those who completed treatment.

ID
2597a0da3b014582
Source org
PubMed Central
Author
Björn Philips (Stockholm University), Jakob Mechler (Uppsala University), Carl-Johan Uckelstam (Stockholm University), Gerhard Andersson (Linköping University), Per Carlbring (Stockholm University), Julian Edbrook-Childs (Anna Freud Centre), Fredrik Falkenström (Linköping University), Robert Johansson (Stockholm University), Peter Lilliengren (Stockholm University), Katja Lindert Bergsten (Uppsala University), Nick Midgley (Anna Freud Centre), Rolf Sandell (Lund University), Agneta Thorén, Naira Topooco (Uppsala University), Randi Ulberg (University of Oslo), Karin Lindqvist (Stockholm University)
Published
2026-02-22
OA status
gold
DOI
10.1016/j.invent.2026.100923
PMID
Not recorded
PMCID
Not recorded
Citations
1

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BibTeX

@article{allodium:2597a0da3b014582,
  title = {Randomized controlled trial on feedback-informed internet-delivered psychodynamic therapy for adolescents with depression: A trial that failed to recruit enough participants},
  author = {Björn Philips and Jakob Mechler and Carl-Johan Uckelstam and Gerhard Andersson and Per Carlbring and Julian Edbrook-Childs and Fredrik Falkenström and Robert Johansson and Peter Lilliengren and Katja Lindert Bergsten and Nick Midgley and Rolf Sandell and Agneta Thorén and Naira Topooco and Randi Ulberg and Karin Lindqvist},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1016/j.invent.2026.100923},
  url = {https://doi.org/10.1016/j.invent.2026.100923}
}

RIS

TY  - JOUR
TI  - Randomized controlled trial on feedback-informed internet-delivered psychodynamic therapy for adolescents with depression: A trial that failed to recruit enough participants
AU  - Philips, Björn
AU  - Mechler, Jakob
AU  - Uckelstam, Carl-Johan
AU  - Andersson, Gerhard
AU  - Carlbring, Per
AU  - Edbrook-Childs, Julian
AU  - Falkenström, Fredrik
AU  - Johansson, Robert
AU  - Lilliengren, Peter
AU  - Bergsten, Katja Lindert
AU  - Midgley, Nick
AU  - Sandell, Rolf
AU  - Thorén, Agneta
AU  - Topooco, Naira
AU  - Ulberg, Randi
AU  - Lindqvist, Karin
PY  - 2026
PB  - PubMed Central
DO  - 10.1016/j.invent.2026.100923
UR  - https://doi.org/10.1016/j.invent.2026.100923
ER  -

APA

Philips, B., Mechler, J., Uckelstam, C., Andersson, G., Carlbring, P., Edbrook-Childs, J., Falkenström, F., Johansson, R., Lilliengren, P., Bergsten, K. L., Midgley, N., Sandell, R., Thorén, A., Topooco, N., Ulberg, R., & Lindqvist, K. (2026). Randomized controlled trial on feedback-informed internet-delivered psychodynamic therapy for adolescents with depression: A trial that failed to recruit enough participants. PubMed Central. https://doi.org/10.1016/j.invent.2026.100923

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