Randomized comparative effectiveness study of 1-session vs 8-session online behavioral treatment for chronic pain: protocol for the national PROGRESS study

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This protocol outlines a randomized non-inferiority trial comparing a single-session online behavioral intervention (Empowered Relief) against an eight-session online cognitive behavioral therapy program for chronic pain. The study aims to recruit 1,200 adults with diverse chronic pain conditions across six sites to assess changes in pain intensity and interference over six months. It is designed to provide comparative effectiveness data to inform patient matching and shared decision-making regarding accessible telehealth treatments.

ID
4244b7800cc74b2e
Source org
PubMed Central
Author
E. M. Monson (Pain Relief Foundation), Aram S. Mardian (University of Phoenix), Kartikeya Saxena (Phoenix VA Health Care System), Brittany Dorsonne (Pain Relief Foundation), Arayam Y Hailu (Pain Relief Foundation), Elizabeth Heggan (Lehigh Valley Hospital-Pocono), Gabrielle Riazi (Dean Health Plan), Kristen Slater (Pain Relief Foundation), Heather Poupore-King (Pain Relief Foundation), Jessica Clifton (California Wellness Foundation), Luzmercy Perez (Pain Relief Foundation), Lu Tian (Palo Alto University), Joel Porter (Intermountain Healthcare), Steve Denton (Lehigh Valley Hospital-Pocono), Eric R. Hanson (Conemaugh Memorial Medical Center), Jackie Miefert (University of Kentucky HealthCare), Beverly E. Thorn (University of Alabama), Sean C Mackey (Pain Cure Center), Matthias Cheung (University of the Pacific), Beth D Darnall (Pain Relief Foundation)
Published
2026-02-18
OA status
hybrid
DOI
10.1093/pm/pnag027
PMID
Not recorded
PMCID
Not recorded
Citations
0

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BibTeX

@article{allodium:4244b7800cc74b2e,
  title = {Randomized comparative effectiveness study of 1-session vs 8-session online behavioral treatment for chronic pain: protocol for the national PROGRESS study},
  author = {E. M. Monson and Aram S. Mardian and Kartikeya Saxena and Brittany Dorsonne and Arayam Y Hailu and Elizabeth Heggan and Gabrielle Riazi and Kristen Slater and Heather Poupore-King and Jessica Clifton and Luzmercy Perez and Lu Tian and Joel Porter and Steve Denton and Eric R. Hanson and Jackie Miefert and Beverly E. Thorn and Sean C Mackey and Matthias Cheung and Beth D Darnall},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1093/pm/pnag027},
  url = {https://doi.org/10.1093/pm/pnag027}
}

RIS

TY  - JOUR
TI  - Randomized comparative effectiveness study of 1-session vs 8-session online behavioral treatment for chronic pain: protocol for the national PROGRESS study
AU  - Monson, E. M.
AU  - Mardian, Aram S.
AU  - Saxena, Kartikeya
AU  - Dorsonne, Brittany
AU  - Hailu, Arayam Y
AU  - Heggan, Elizabeth
AU  - Riazi, Gabrielle
AU  - Slater, Kristen
AU  - Poupore-King, Heather
AU  - Clifton, Jessica
AU  - Perez, Luzmercy
AU  - Tian, Lu
AU  - Porter, Joel
AU  - Denton, Steve
AU  - Hanson, Eric R.
AU  - Miefert, Jackie
AU  - Thorn, Beverly E.
AU  - Mackey, Sean C
AU  - Cheung, Matthias
AU  - Darnall, Beth D
PY  - 2026
PB  - PubMed Central
DO  - 10.1093/pm/pnag027
UR  - https://doi.org/10.1093/pm/pnag027
ER  - 

APA

Monson, E. M., Mardian, A. S., Saxena, K., Dorsonne, B., Hailu, A. Y., Heggan, E., Riazi, G., Slater, K., Poupore-King, H., Clifton, J., Perez, L., Tian, L., Porter, J., Denton, S., Hanson, E. R., Miefert, J., Thorn, B. E., Mackey, S. C., Cheung, M., & Darnall, B. D. (2026). Randomized comparative effectiveness study of 1-session vs 8-session online behavioral treatment for chronic pain: protocol for the national PROGRESS study. PubMed Central. https://doi.org/10.1093/pm/pnag027

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