Research protocol of the efficacy of probiotics for the treatment of alcohol use disorder among adult males: A comparison with placebo and acceptance and commitment therapy in a randomized controlled trial

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This research protocol outlines a randomized controlled trial comparing the efficacy of probiotics and acceptance and commitment therapy (ACT) against placebo for treating alcohol use disorder in adult males post-detoxification. The study aims to assess primary outcomes related to alcohol craving and disorder severity, alongside secondary measures including comorbid depression, anxiety, inflammatory cytokine levels, EEG changes, and gut microbiota composition. It is designed for researchers and clinicians interested in the methodological framework of this specific clinical investigation.

ID
599a4253880f4c1a
Source org
OpenAlex
Author
Bingyu Zhang (Universiti Sains Malaysia), Ruiling Zhang (Henan Medical University), Hongdu Deng (Universiti Sains Malaysia), Ping Cui (Henan Medical University), Chunyan Li (Henan Medical University), Fan Yang (Henan Medical University), Mohammad Farris Iman Leong Bin Abdullah (Universiti Sains Malaysia)
Published
2023-12-05
OA status
gold
DOI
10.1371/journal.pone.0294768
PMID
Not recorded
PMCID
Not recorded
Citations
6

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BibTeX

@article{allodium:599a4253880f4c1a,
  title = {Research protocol of the efficacy of probiotics for the treatment of alcohol use disorder among adult males: A comparison with placebo and acceptance and commitment therapy in a randomized controlled trial},
  author = {Bingyu Zhang and Ruiling Zhang and Hongdu Deng and Ping Cui and Chunyan Li and Fan Yang and Mohammad Farris Iman Leong Bin Abdullah},
  year = {2023},
  journal = {OpenAlex},
  doi = {10.1371/journal.pone.0294768},
  url = {https://doi.org/10.1371/journal.pone.0294768}
}

RIS

TY  - JOUR
TI  - Research protocol of the efficacy of probiotics for the treatment of alcohol use disorder among adult males: A comparison with placebo and acceptance and commitment therapy in a randomized controlled trial
AU  - Zhang, Bingyu
AU  - Zhang, Ruiling
AU  - Deng, Hongdu
AU  - Cui, Ping
AU  - Li, Chunyan
AU  - Yang, Fan
AU  - Abdullah, Mohammad Farris Iman Leong Bin
PY  - 2023
PB  - OpenAlex
DO  - 10.1371/journal.pone.0294768
UR  - https://doi.org/10.1371/journal.pone.0294768
ER  -

APA

Zhang, B., Zhang, R., Deng, H., Cui, P., Li, C., Yang, F., & Abdullah, M. F. I. L. B. (2023). Research protocol of the efficacy of probiotics for the treatment of alcohol use disorder among adult males: A comparison with placebo and acceptance and commitment therapy in a randomized controlled trial. OpenAlex. https://doi.org/10.1371/journal.pone.0294768

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