MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study

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This phase 3 randomized controlled trial evaluates the efficacy and safety of MDMA-assisted therapy for severe PTSD, including patients with common comorbidities. The study compares manualized therapy combined with MDMA against a placebo control, measuring outcomes via CAPS-5 and Sheehan Disability Scale scores at baseline and two months post-treatment. Results indicate significant symptom reduction and functional improvement in the MDMA group compared to placebo, with no observed increase in abuse potential or suicidality.

ID
5da90e8f47a644cd
Source org
OpenAlex
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DOI
10.1038/s41591-021-01336-3
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BibTeX

@article{allodium:5da90e8f47a644cd,
  title = {MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study},
  journal = {OpenAlex},
  doi = {10.1038/s41591-021-01336-3},
  url = {https://doi.org/10.1038/s41591-021-01336-3}
}

RIS

TY  - JOUR
TI  - MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study
PB  - OpenAlex
DO  - 10.1038/s41591-021-01336-3
UR  - https://doi.org/10.1038/s41591-021-01336-3
ER  -

APA

MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study. (n.d.). OpenAlex. https://doi.org/10.1038/s41591-021-01336-3

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