Family-based cognitive behavioral therapy versus family-based psychoeducation and relaxation training for obsessive-compulsive disorder in children and adolescents: a randomized clinical trial (TECTO)

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This randomized clinical trial compares family-based cognitive behavioral therapy with exposure and response prevention against family-based psychoeducation and relaxation training for children and adolescents aged 8–17 with obsessive-compulsive disorder. The study reports that while the CBT group showed significantly greater symptom reduction than the control group, the difference was modest and fell below the predefined threshold for clinical importance. The resource details the trial's methodology, participant demographics, and adverse event monitoring to assess tolerability.

ID
67b0281a65a74ada
Source org
PubMed Central
Author
Anne Katrine Pagsberg (University of Copenhagen), Nicole Nadine Lønfeldt (Mental Health Services), Christine Lykke Thoustrup (Mental Health Services), Nicoline Løcke Jepsen Korsbjerg (University of Copenhagen), Camilla Uhre (Mental Health Services), Sofie Heidenheim Christensen (University of Copenhagen), Valdemar Uhre (Mental Health Services), Anna‐Rosa Cecilie Mora‐Jensen (Mental Health Services), Melanie Ritter (University of Copenhagen), Linea Pretzmann (University of Copenhagen), Helga Kristensen Ingstrup (Mental Health Services), Birgitte Borgbjerg Moltke (Psychiatry Region Zealand), Gitte Sommer Harboe (Mental Health Services), Emilie Damløv Thorsen (Mental Health Services), Line Katrine Harder Clemmensen (Department of Mathematical Sciences), Jane Lindschou (Copenhagen University Hospital), Janus Engstrøm (Copenhagen University Hospital), Christian Gluud (University of Southern Denmark), Hartwig R. Siebner (University of Copenhagen), Per Hove Thomsen (Aarhus University), Katja Anna Hybel (Aarhus University Hospital), Frank C. Verhulst (Mental Health Services), William F.C. Baaré (Copenhagen University Hospital), Pia Jeppesen (University of Copenhagen), Jens Richardt Møllegaard Jepsen (Mental Health Services)
Published
2025-07-31
OA status
hybrid
DOI
10.1007/s00787-025-02797-4
PMID
Not recorded
PMCID
Not recorded
Citations
1

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BibTeX

@article{allodium:67b0281a65a74ada,
  title = {Family-based cognitive behavioral therapy versus family-based psychoeducation and relaxation training for obsessive-compulsive disorder in children and adolescents: a randomized clinical trial (TECTO)},
  author = {Anne Katrine Pagsberg and Nicole Nadine Lønfeldt and Christine Lykke Thoustrup and Nicoline Løcke Jepsen Korsbjerg and Camilla Uhre and Sofie Heidenheim Christensen and Valdemar Uhre and Anna‐Rosa Cecilie Mora‐Jensen and Melanie Ritter and Linea Pretzmann and Helga Kristensen Ingstrup and Birgitte Borgbjerg Moltke and Gitte Sommer Harboe and Emilie Damløv Thorsen and Line Katrine Harder Clemmensen and Jane Lindschou and Janus Engstrøm and Christian Gluud and Hartwig R. Siebner and Per Hove Thomsen and Katja Anna Hybel and Frank C. Verhulst and William F.C. Baaré and Pia Jeppesen and Jens Richardt Møllegaard Jepsen},
  year = {2025},
  journal = {PubMed Central},
  doi = {10.1007/s00787-025-02797-4},
  url = {https://doi.org/10.1007/s00787-025-02797-4}
}

RIS

TY  - JOUR
TI  - Family-based cognitive behavioral therapy versus family-based psychoeducation and relaxation training for obsessive-compulsive disorder in children and adolescents: a randomized clinical trial (TECTO)
AU  - Pagsberg, Anne Katrine
AU  - Lønfeldt, Nicole Nadine
AU  - Thoustrup, Christine Lykke
AU  - Korsbjerg, Nicoline Løcke Jepsen
AU  - Uhre, Camilla
AU  - Christensen, Sofie Heidenheim
AU  - Uhre, Valdemar
AU  - Mora‐Jensen, Anna‐Rosa Cecilie
AU  - Ritter, Melanie
AU  - Pretzmann, Linea
AU  - Ingstrup, Helga Kristensen
AU  - Moltke, Birgitte Borgbjerg
AU  - Harboe, Gitte Sommer
AU  - Thorsen, Emilie Damløv
AU  - Clemmensen, Line Katrine Harder
AU  - Lindschou, Jane
AU  - Engstrøm, Janus
AU  - Gluud, Christian
AU  - Siebner, Hartwig R.
AU  - Thomsen, Per Hove
AU  - Hybel, Katja Anna
AU  - Verhulst, Frank C.
AU  - Baaré, William F.C.
AU  - Jeppesen, Pia
AU  - Jepsen, Jens Richardt Møllegaard
PY  - 2025
PB  - PubMed Central
DO  - 10.1007/s00787-025-02797-4
UR  - https://doi.org/10.1007/s00787-025-02797-4
ER  -

APA

Pagsberg, A. K., Lønfeldt, N. N., Thoustrup, C. L., Korsbjerg, N. L. J., Uhre, C., Christensen, S. H., Uhre, V., Mora‐Jensen, A. C., Ritter, M., Pretzmann, L., Ingstrup, H. K., Moltke, B. B., Harboe, G. S., Thorsen, E. D., Clemmensen, L. K. H., Lindschou, J., Engstrøm, J., Gluud, C., Siebner, H. R., Thomsen, P. H., Hybel, K. A., Verhulst, F. C., Baaré, W. F., Jeppesen, P., & Jepsen, J. R. M. (2025). Family-based cognitive behavioral therapy versus family-based psychoeducation and relaxation training for obsessive-compulsive disorder in children and adolescents: a randomized clinical trial (TECTO). PubMed Central. https://doi.org/10.1007/s00787-025-02797-4

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