The Effect of Internet-Based Cognitive Behavioral Therapy (I-CBT) for Severe Fatigue in Adolescents with Immune Dysregulation Disorders: Preliminary Findings using a Multiple Single-Case Experimental Design

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This study evaluates the impact of internet-based cognitive behavioral therapy on severe fatigue in nine adolescents with immune dysregulation disorders using a single-case experimental design. The research measures changes in fatigue severity, physical functioning, and school absence before treatment, during the intervention, and at follow-up. Results indicate significant group-level improvements in fatigue and physical functioning, with individual case analyses showing varied but positive outcomes for most participants.

ID
68c9b6137c7c4ad6
Source org
PubMed Central
Author
Linde N. Nijhof (Wilhelmina Children's Hospital), Anouk Vroegindeweij (Wilhelmina Children's Hospital), Jan Houtveen (Wilhelmina Children's Hospital), Hans Knoop (Amsterdam University Medical Centers), Joris M. van Montfrans (Wilhelmina Children's Hospital), Patrick Onghena (KU Leuven), Elise M. van de Putte (Wilhelmina Children's Hospital), Sanne L. Nijhof (Wilhelmina Children's Hospital)
Published
2025-10-22
OA status
hybrid
DOI
10.1007/s10880-025-10096-y
PMID
Not recorded
PMCID
Not recorded
Citations
1

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BibTeX

@article{allodium:68c9b6137c7c4ad6,
  title = {The Effect of Internet-Based Cognitive Behavioral Therapy (I-CBT) for Severe Fatigue in Adolescents with Immune Dysregulation Disorders: Preliminary Findings using a Multiple Single-Case Experimental Design},
  author = {Linde N. Nijhof and Anouk Vroegindeweij and Jan Houtveen and Hans Knoop and Joris M. van Montfrans and Patrick Onghena and Elise M. van de Putte and Sanne L. Nijhof},
  year = {2025},
  journal = {PubMed Central},
  doi = {10.1007/s10880-025-10096-y},
  url = {https://doi.org/10.1007/s10880-025-10096-y}
}

RIS

TY  - JOUR
TI  - The Effect of Internet-Based Cognitive Behavioral Therapy (I-CBT) for Severe Fatigue in Adolescents with Immune Dysregulation Disorders: Preliminary Findings using a Multiple Single-Case Experimental Design
AU  - Nijhof, Linde N.
AU  - Vroegindeweij, Anouk
AU  - Houtveen, Jan
AU  - Knoop, Hans
AU  - Montfrans, Joris M. van
AU  - Onghena, Patrick
AU  - Putte, Elise M. van de
AU  - Nijhof, Sanne L.
PY  - 2025
PB  - PubMed Central
DO  - 10.1007/s10880-025-10096-y
UR  - https://doi.org/10.1007/s10880-025-10096-y
ER  - 

APA

Nijhof, L. N., Vroegindeweij, A., Houtveen, J., Knoop, H., Montfrans, J. M. V., Onghena, P., Putte, E. M. V. D., & Nijhof, S. L. (2025). The Effect of Internet-Based Cognitive Behavioral Therapy (I-CBT) for Severe Fatigue in Adolescents with Immune Dysregulation Disorders: Preliminary Findings using a Multiple Single-Case Experimental Design. PubMed Central. https://doi.org/10.1007/s10880-025-10096-y

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