The Effect of Internet-Based Cognitive Behavioral Therapy (I-CBT) for Severe Fatigue in Adolescents with Immune Dysregulation Disorders: Preliminary Findings using a Multiple Single-Case Experimental Design
Overview
This study evaluates the impact of internet-based cognitive behavioral therapy on severe fatigue in nine adolescents with immune dysregulation disorders using a single-case experimental design. The research measures changes in fatigue severity, physical functioning, and school absence before treatment, during the intervention, and at follow-up. Results indicate significant group-level improvements in fatigue and physical functioning, with individual case analyses showing varied but positive outcomes for most participants.
- ID
68c9b6137c7c4ad6- Source org
- PubMed Central
- Author
- Linde N. Nijhof (Wilhelmina Children's Hospital), Anouk Vroegindeweij (Wilhelmina Children's Hospital), Jan Houtveen (Wilhelmina Children's Hospital), Hans Knoop (Amsterdam University Medical Centers), Joris M. van Montfrans (Wilhelmina Children's Hospital), Patrick Onghena (KU Leuven), Elise M. van de Putte (Wilhelmina Children's Hospital), Sanne L. Nijhof (Wilhelmina Children's Hospital)
- Published
- 2025-10-22
- OA status
- hybrid
- DOI
- 10.1007/s10880-025-10096-y
- PMID
- Not recorded
- PMCID
- Not recorded
- Citations
- 1
Tags
Verification
- identityok via crossref · score 1 · checked_at unknown
- legitimacykeep via unknown · score 1 · checked_at unknown
- linkok via http-check · 2026-07-21T15:52:31.592259+00:00
Cite this entry
BibTeX
@article{allodium:68c9b6137c7c4ad6,
title = {The Effect of Internet-Based Cognitive Behavioral Therapy (I-CBT) for Severe Fatigue in Adolescents with Immune Dysregulation Disorders: Preliminary Findings using a Multiple Single-Case Experimental Design},
author = {Linde N. Nijhof and Anouk Vroegindeweij and Jan Houtveen and Hans Knoop and Joris M. van Montfrans and Patrick Onghena and Elise M. van de Putte and Sanne L. Nijhof},
year = {2025},
journal = {PubMed Central},
doi = {10.1007/s10880-025-10096-y},
url = {https://doi.org/10.1007/s10880-025-10096-y}
}RIS
TY - JOUR TI - The Effect of Internet-Based Cognitive Behavioral Therapy (I-CBT) for Severe Fatigue in Adolescents with Immune Dysregulation Disorders: Preliminary Findings using a Multiple Single-Case Experimental Design AU - Nijhof, Linde N. AU - Vroegindeweij, Anouk AU - Houtveen, Jan AU - Knoop, Hans AU - Montfrans, Joris M. van AU - Onghena, Patrick AU - Putte, Elise M. van de AU - Nijhof, Sanne L. PY - 2025 PB - PubMed Central DO - 10.1007/s10880-025-10096-y UR - https://doi.org/10.1007/s10880-025-10096-y ER -
APA
Nijhof, L. N., Vroegindeweij, A., Houtveen, J., Knoop, H., Montfrans, J. M. V., Onghena, P., Putte, E. M. V. D., & Nijhof, S. L. (2025). The Effect of Internet-Based Cognitive Behavioral Therapy (I-CBT) for Severe Fatigue in Adolescents with Immune Dysregulation Disorders: Preliminary Findings using a Multiple Single-Case Experimental Design. PubMed Central. https://doi.org/10.1007/s10880-025-10096-y
Related entries
- Efficacy of Cognitive-Behavioral Therapy Targeting Severe Fatigue Following Coronavirus Disease 2019: Results of a Randomized Controlled Trial
- Transdiagnostic cognitive behavioral therapy for severe and persistent fatigue – a feasibility study in primary care
- Internet-delivered cognitive behavior therapy for children and adolescents: A systematic review and meta-analysis
- Effects of Cognitive Behavior Therapy in Severely Fatigued Disease-Free Cancer Patients Compared With Patients Waiting for Cognitive Behavior Therapy: A Randomized Controlled Trial
- Mindfulness‐Based Cognitive Therapy for People with Chronic Fatigue Syndrome Still Experiencing Excessive Fatigue after Cognitive Behaviour Therapy: A Pilot Randomized Study
- Feasibility and acceptability of therapist-guided, asynchronous, internet-delivered trauma-focused CBT for adolescents with PTSD: a single-group feasibility trial in Sweden
- Developmentally Tailored Telehealth-Delivered Cognitive-Behavioural Therapy for Adolescents with Body Dysmorphic Disorder: A Multiple Baseline Design
- Long-term effectiveness of cognitive behavioral therapy (CBT) for children and adolescents in routine care
- Patient experiences with internet-based cognitive behavioral therapy for multi-system functional somatic disorder: A qualitative study
- A Pilot Randomized Controlled Trial of Cognitive-Behavioral Therapy for Adolescents With Body Dysmorphic Disorder