The nature of depression and the biomedical model: ten questions in search of an answer

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This paper addresses ten questions regarding the nature of depression and the biomedical model, arguing that depression is a dysfunction in mood regulation rather than a functional stress reaction. The author contends that while psychosocial approaches face methodological challenges, psychotherapies likely operate through generic pathways involving compassion and practical interventions. The text concludes that future progress requires integrating neuroscience advances with strong psychosocial elements and patient education.

ID
7116b6720ab64fbe
Source org
PubMed Central
Author
K. N. Fountoulakis (Aristotle University of Thessaloniki)
Published
2026-03-18
OA status
gold
DOI
10.1038/s41398-026-03943-5
PMID
Not recorded
PMCID
Not recorded
Citations
1

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BibTeX

@article{allodium:7116b6720ab64fbe,
  title = {The nature of depression and the biomedical model: ten questions in search of an answer},
  author = {K. N. Fountoulakis},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1038/s41398-026-03943-5},
  url = {https://doi.org/10.1038/s41398-026-03943-5}
}

RIS

TY  - JOUR
TI  - The nature of depression and the biomedical model: ten questions in search of an answer
AU  - Fountoulakis, K. N.
PY  - 2026
PB  - PubMed Central
DO  - 10.1038/s41398-026-03943-5
UR  - https://doi.org/10.1038/s41398-026-03943-5
ER  -

APA

Fountoulakis, K. N. (2026). The nature of depression and the biomedical model: ten questions in search of an answer. PubMed Central. https://doi.org/10.1038/s41398-026-03943-5

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