Mindfulness-based cognitive therapy for patients with chronic, treatment-resistant depression: A pragmatic randomized controlled trial

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This randomized controlled trial evaluates the efficacy of Mindfulness-Based Cognitive Therapy (MBCT) combined with treatment-as-usual for 106 outpatients with chronic, treatment-resistant depression. The study reports that while the intention-to-treat analysis did not show a significant reduction in depressive symptoms compared to control, the MBCT group demonstrated higher remission rates and improvements in rumination, quality of life, mindfulness skills, and self-compassion. Per-protocol analyses indicated that participants who completed the program experienced significantly fewer depressive symptoms than those receiving standard care alone.

ID
7da2d0ca7d8d455b
Source org
OpenAlex
Author
Mira B. Cladder-Micus (Radboud University Nijmegen), Anne E.M. Speckens (Radboud University Nijmegen), Janna N. Vrijsen (Radboud University Nijmegen), A. Rogier T. Donders (Radboud University Nijmegen), Eni S. Becker (Radboud University Nijmegen), Jan Spijker (Radboud University Nijmegen)
Published
2018-08-08
OA status
hybrid
DOI
10.1002/da.22788
PMID
Not recorded
PMCID
Not recorded
Citations
139

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BibTeX

@article{allodium:7da2d0ca7d8d455b,
  title = {Mindfulness-based cognitive therapy for patients with chronic, treatment-resistant depression: A pragmatic randomized controlled trial},
  author = {Mira B. Cladder-Micus and Anne E.M. Speckens and Janna N. Vrijsen and A. Rogier T. Donders and Eni S. Becker and Jan Spijker},
  year = {2018},
  journal = {OpenAlex},
  doi = {10.1002/da.22788},
  url = {https://doi.org/10.1002/da.22788}
}

RIS

TY  - JOUR
TI  - Mindfulness-based cognitive therapy for patients with chronic, treatment-resistant depression: A pragmatic randomized controlled trial
AU  - Cladder-Micus, Mira B.
AU  - Speckens, Anne E.M.
AU  - Vrijsen, Janna N.
AU  - Donders, A. Rogier T.
AU  - Becker, Eni S.
AU  - Spijker, Jan
PY  - 2018
PB  - OpenAlex
DO  - 10.1002/da.22788
UR  - https://doi.org/10.1002/da.22788
ER  -

APA

Cladder-Micus, M. B., Speckens, A. E., Vrijsen, J. N., Donders, A. R. T., Becker, E. S., & Spijker, J. (2018). Mindfulness-based cognitive therapy for patients with chronic, treatment-resistant depression: A pragmatic randomized controlled trial. OpenAlex. https://doi.org/10.1002/da.22788

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