MicroRNAs expression changes associated with trauma-focused psychotherapy efficacy in treatment-resistant depression: An exploratory study

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This exploratory study investigates plasma microRNA changes in 24 patients with treatment-resistant depression and a history of early life stress following eight weeks of trauma-focused cognitive behavioral therapy or EMDR. The research identifies specific miRNAs, such as miR-132-3p, that are downregulated after treatment and correlates these molecular shifts with improvements in depressive symptoms. The resource is intended for researchers interested in the epigenetic mechanisms underlying psychotherapy efficacy.

ID
82f309aa1ac2490f
Source org
PubMed Central
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DOI
10.1016/j.nsa.2026.107020
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BibTeX

@article{allodium:82f309aa1ac2490f,
  title = {MicroRNAs expression changes associated with trauma-focused psychotherapy efficacy in treatment-resistant depression: An exploratory study},
  journal = {PubMed Central},
  doi = {10.1016/j.nsa.2026.107020},
  url = {https://doi.org/10.1016/j.nsa.2026.107020}
}

RIS

TY  - JOUR
TI  - MicroRNAs expression changes associated with trauma-focused psychotherapy efficacy in treatment-resistant depression: An exploratory study
PB  - PubMed Central
DO  - 10.1016/j.nsa.2026.107020
UR  - https://doi.org/10.1016/j.nsa.2026.107020
ER  -

APA

MicroRNAs expression changes associated with trauma-focused psychotherapy efficacy in treatment-resistant depression: An exploratory study. (n.d.). PubMed Central. https://doi.org/10.1016/j.nsa.2026.107020

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