Effect of app-based mindfulness on extinction recall – a 7T-fMRI study

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This randomized controlled trial investigates how app-based mindfulness meditation influences fear extinction recall using 7T-fMRI in healthy participants. The study compares a group receiving four weeks of mindfulness training against a waitlist control to assess changes in physiological and neural threat responses. Results indicate that mindfulness enhanced the retrieval of safety memories by reducing activation in subcortical threat-processing regions, suggesting a mechanism distinct from top-down cognitive inhibition.

ID
bbeb9f8252304c40
Source org
PubMed Central
Author
Johannes Björkstrand (Lund University), Emil Olsson (Lund University), O. Clancy (Lund University), Stefan Möller (Lund University), Isabella M Björkman-Burtscher (Sahlgrenska University Hospital), Nishika Raheja (Biomedical Research Institute), David Sjöström (Lund University), Marino Theodor Larsen Persiani (University of Southern Denmark), Walter Staiano (Universitat de València), Ulrich Kirk (University of Southern Denmark)
Published
2026-03-25
OA status
gold
DOI
10.1038/s41598-026-45569-z
PMID
Not recorded
PMCID
Not recorded
Citations
1

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BibTeX

@article{allodium:bbeb9f8252304c40,
  title = {Effect of app-based mindfulness on extinction recall – a 7T-fMRI study},
  author = {Johannes Björkstrand and Emil Olsson and O. Clancy and Stefan Möller and Isabella M Björkman-Burtscher and Nishika Raheja and David Sjöström and Marino Theodor Larsen Persiani and Walter Staiano and Ulrich Kirk},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1038/s41598-026-45569-z},
  url = {https://doi.org/10.1038/s41598-026-45569-z}
}

RIS

TY  - JOUR
TI  - Effect of app-based mindfulness on extinction recall – a 7T-fMRI study
AU  - Björkstrand, Johannes
AU  - Olsson, Emil
AU  - Clancy, O.
AU  - Möller, Stefan
AU  - Björkman-Burtscher, Isabella M
AU  - Raheja, Nishika
AU  - Sjöström, David
AU  - Persiani, Marino Theodor Larsen
AU  - Staiano, Walter
AU  - Kirk, Ulrich
PY  - 2026
PB  - PubMed Central
DO  - 10.1038/s41598-026-45569-z
UR  - https://doi.org/10.1038/s41598-026-45569-z
ER  -

APA

Björkstrand, J., Olsson, E., Clancy, O., Möller, S., Björkman-Burtscher, I. M., Raheja, N., Sjöström, D., Persiani, M. T. L., Staiano, W., & Kirk, U. (2026). Effect of app-based mindfulness on extinction recall – a 7T-fMRI study. PubMed Central. https://doi.org/10.1038/s41598-026-45569-z

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