Therapeutic Improvement in People With Schizophrenia Undergoing tACS/CBTp (Transcranial Alternating Current Stimulation/Cognitive Behavioral Therapy for Psychosis) Associated With Usual Medication Regimen: Protocol for a Pilot, Randomized, Single-Blind Trial

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This protocol outlines a pilot, randomized, single-blind trial investigating the addition of transcranial alternating current stimulation (tACS) to cognitive behavioral therapy for psychosis (CBTp) in individuals with schizophrenia who are on their usual medication regimen. The study aims to evaluate whether tACS augments CBTp efficacy regarding functioning levels and symptom improvement, while also assessing potential gender-specific responses. It involves 28 participants assigned to either active or sham tACS combined with CBTp over 16 weeks, with outcomes measured via electroencephalogram and clinical scales.

ID
cdecbe72f68e4e2b
Source org
PubMed Central
Author
Felicia Iftene (Providence Health Care), Adriana Farcas (Queen's University), Simon O’Brien (Providence Health Care), Christopher R. Bowie (Queen's University), Michael Best (University of Toronto), Oyedeji Ayonrinde (Queen's University), Terry Landry (Providence Health Care), Jennifer Carlson (Queen's University), Scott John Davidson (Queen's University), Ellie Rodgerson (Queen's University), Ashley Theis (Queen's University)
Published
2025-11-21
OA status
gold
DOI
10.2196/80593
PMID
Not recorded
PMCID
Not recorded
Citations
0

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BibTeX

@article{allodium:cdecbe72f68e4e2b,
  title = {Therapeutic Improvement in People With Schizophrenia Undergoing tACS/CBTp (Transcranial Alternating Current Stimulation/Cognitive Behavioral Therapy for Psychosis) Associated With Usual Medication Regimen: Protocol for a Pilot, Randomized, Single-Blind Trial},
  author = {Felicia Iftene and Adriana Farcas and Simon O’Brien and Christopher R. Bowie and Michael Best and Oyedeji Ayonrinde and Terry Landry and Jennifer Carlson and Scott John Davidson and Ellie Rodgerson and Ashley Theis},
  year = {2025},
  journal = {PubMed Central},
  doi = {10.2196/80593},
  url = {https://doi.org/10.2196/80593}
}

RIS

TY  - JOUR
TI  - Therapeutic Improvement in People With Schizophrenia Undergoing tACS/CBTp (Transcranial Alternating Current Stimulation/Cognitive Behavioral Therapy for Psychosis) Associated With Usual Medication Regimen: Protocol for a Pilot, Randomized, Single-Blind Trial
AU  - Iftene, Felicia
AU  - Farcas, Adriana
AU  - O’Brien, Simon
AU  - Bowie, Christopher R.
AU  - Best, Michael
AU  - Ayonrinde, Oyedeji
AU  - Landry, Terry
AU  - Carlson, Jennifer
AU  - Davidson, Scott John
AU  - Rodgerson, Ellie
AU  - Theis, Ashley
PY  - 2025
PB  - PubMed Central
DO  - 10.2196/80593
UR  - https://doi.org/10.2196/80593
ER  -

APA

Iftene, F., Farcas, A., O’Brien, S., Bowie, C. R., Best, M., Ayonrinde, O., Landry, T., Carlson, J., Davidson, S. J., Rodgerson, E., & Theis, A. (2025). Therapeutic Improvement in People With Schizophrenia Undergoing tACS/CBTp (Transcranial Alternating Current Stimulation/Cognitive Behavioral Therapy for Psychosis) Associated With Usual Medication Regimen: Protocol for a Pilot, Randomized, Single-Blind Trial. PubMed Central. https://doi.org/10.2196/80593

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