Treatment effect modifiers of virtual reality-based versus standard cognitive behavioral therapy for paranoia in schizophrenia spectrum disorders: an exploratory moderator analysis of clinical and demographic characteristics in the FaceYourFears trial
Overview
This exploratory moderator analysis of the FaceYourFears trial examines how baseline clinical characteristics influence treatment outcomes for paranoia in schizophrenia spectrum disorders comparing virtual reality-based CBT (VR-CBTp) and standard CBTp. The study identifies that individuals with high avolition or moderate-to-high delusion severity showed greater improvement with VR-CBTp, while those with lower delusion severity fared better with standard CBTp. Demographic factors and other clinical variables did not significantly modify treatment effects, suggesting both modalities may be suitable for a broad patient population.
- ID
d6dda4bf1ede4e58- Source org
- PubMed Central
- Author
- Mads Juul Christensen (Aalborg University Hospital), Ditte Lammers Vernal (Aalborg University Hospital), Ulrik Nykjaer Jeppesen (University of Copenhagen), Carsten Hjorthøj (University of Copenhagen), Jan Mainz (University of Southern Denmark), Amy Pinkham, Stephen F. Austin (University of Copenhagen), Wim Veling (University of Groningen), Thomas Ward (King's College London), Merete Nordentoft (University of Copenhagen), Louise Birkedal Glenthøj (University of Copenhagen)
- Published
- 2026-01-01
- OA status
- hybrid
- DOI
- 10.1017/S0033291726103870
- PMID
- Not recorded
- PMCID
- Not recorded
- Citations
- 1
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Cite this entry
BibTeX
@article{allodium:d6dda4bf1ede4e58,
title = {Treatment effect modifiers of virtual reality-based versus standard cognitive behavioral therapy for paranoia in schizophrenia spectrum disorders: an exploratory moderator analysis of clinical and demographic characteristics in the FaceYourFears trial},
author = {Mads Juul Christensen and Ditte Lammers Vernal and Ulrik Nykjaer Jeppesen and Carsten Hjorthøj and Jan Mainz and Amy Pinkham and Stephen F. Austin and Wim Veling and Thomas Ward and Merete Nordentoft and Louise Birkedal Glenthøj},
year = {2026},
journal = {PubMed Central},
doi = {10.1017/S0033291726103870},
url = {https://doi.org/10.1017/S0033291726103870}
}RIS
TY - JOUR TI - Treatment effect modifiers of virtual reality-based versus standard cognitive behavioral therapy for paranoia in schizophrenia spectrum disorders: an exploratory moderator analysis of clinical and demographic characteristics in the FaceYourFears trial AU - Christensen, Mads Juul AU - Vernal, Ditte Lammers AU - Jeppesen, Ulrik Nykjaer AU - Hjorthøj, Carsten AU - Mainz, Jan AU - Pinkham, Amy AU - Austin, Stephen F. AU - Veling, Wim AU - Ward, Thomas AU - Nordentoft, Merete AU - Glenthøj, Louise Birkedal PY - 2026 PB - PubMed Central DO - 10.1017/S0033291726103870 UR - https://doi.org/10.1017/S0033291726103870 ER -
APA
Christensen, M. J., Vernal, D. L., Jeppesen, U. N., Hjorthøj, C., Mainz, J., Pinkham, A., Austin, S. F., Veling, W., Ward, T., Nordentoft, M., & Glenthøj, L. B. (2026). Treatment effect modifiers of virtual reality-based versus standard cognitive behavioral therapy for paranoia in schizophrenia spectrum disorders: an exploratory moderator analysis of clinical and demographic characteristics in the FaceYourFears trial. PubMed Central. https://doi.org/10.1017/S0033291726103870
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