Cognitive Behavior Therapy May Sustain Antidepressant Effects of Intravenous Ketamine in Treatment-Resistant Depression

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This open-label trial investigates whether cognitive behavioral therapy (CBT) can extend the antidepressant effects of intravenous ketamine in patients with treatment-resistant depression. The study involved 16 participants who received a short course of ketamine alongside a concurrent 12-session CBT program. Results indicated that while some responders maintained remission for several weeks after treatment, relapse occurred within months for most, and nonresponders did not benefit from the added therapy.

ID
00b16ed17c744069
Source org
OpenAlex
Author
Samuel T. Wilkinson (Yale University), DaShaun Wright (Yale University), Madonna Fasula (Yale University), Lisa R. Fenton (Veterans Health Administration), Matthew Griepp (Yale University), Robert Ostroff (Yale University), Gerard Sanacora (Yale University)
Published
2017-01-01
OA status
bronze
DOI
10.1159/000457960
PMID
Not recorded
PMCID
Not recorded
Citations
122

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BibTeX

@article{allodium:00b16ed17c744069,
  title = {Cognitive Behavior Therapy May Sustain Antidepressant Effects of Intravenous Ketamine in Treatment-Resistant Depression},
  author = {Samuel T. Wilkinson and DaShaun Wright and Madonna Fasula and Lisa R. Fenton and Matthew Griepp and Robert Ostroff and Gerard Sanacora},
  year = {2017},
  journal = {OpenAlex},
  doi = {10.1159/000457960},
  url = {https://doi.org/10.1159/000457960}
}

RIS

TY  - JOUR
TI  - Cognitive Behavior Therapy May Sustain Antidepressant Effects of Intravenous Ketamine in Treatment-Resistant Depression
AU  - Wilkinson, Samuel T.
AU  - Wright, DaShaun
AU  - Fasula, Madonna
AU  - Fenton, Lisa R.
AU  - Griepp, Matthew
AU  - Ostroff, Robert
AU  - Sanacora, Gerard
PY  - 2017
PB  - OpenAlex
DO  - 10.1159/000457960
UR  - https://doi.org/10.1159/000457960
ER  -

APA

Wilkinson, S. T., Wright, D., Fasula, M., Fenton, L. R., Griepp, M., Ostroff, R., & Sanacora, G. (2017). Cognitive Behavior Therapy May Sustain Antidepressant Effects of Intravenous Ketamine in Treatment-Resistant Depression. OpenAlex. https://doi.org/10.1159/000457960

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