Comparative benefits and harms of second generation antidepressants and cognitive behavioral therapies in initial treatment of major depressive disorder: systematic review and meta-analysis

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This systematic review and meta-analysis compares the benefits and harms of second-generation antidepressants versus cognitive behavioral therapy for adults with major depressive disorder. The authors analyzed eleven randomized controlled trials to assess differences in treatment response, remission rates, and discontinuation due to adverse events or lack of efficacy. The resource indicates that no statistically significant differences were found between the two treatments for most measured outcomes, though the evidence strength was generally low.

ID
b71c4175c6374f9a
Source org
OpenAlex
Author
Halle R Amick (University of North Carolina at Chapel Hill), Gerald Gartlehner (Universität für Weiterbildung Krems), Bradley N. Gaynes (University of North Carolina at Chapel Hill), Catherine A Forneris (University of North Carolina at Chapel Hill), Gary Asher (University of North Carolina at Chapel Hill), Laura C Morgan (RTI International), Emmanuel Coker‐Schwimmer (University of North Carolina at Chapel Hill), Erin Boland (RTI International), Linda J Lux (RTI International), Susan Gaylord (University of North Carolina at Chapel Hill), Carla Bann (RTI International), Christiane Barbara Pierl (Universität für Weiterbildung Krems), Kathleen N Lohr (RTI International)
Published
2015-12-08
OA status
hybrid
DOI
10.1136/bmj.h6019
PMID
Not recorded
PMCID
Not recorded
Citations
180

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BibTeX

@article{allodium:b71c4175c6374f9a,
  title = {Comparative benefits and harms of second generation antidepressants and cognitive behavioral therapies in initial treatment of major depressive disorder: systematic review and meta-analysis},
  author = {Halle R Amick and Gerald Gartlehner and Bradley N. Gaynes and Catherine A Forneris and Gary Asher and Laura C Morgan and Emmanuel Coker‐Schwimmer and Erin Boland and Linda J Lux and Susan Gaylord and Carla Bann and Christiane Barbara Pierl and Kathleen N Lohr},
  year = {2015},
  journal = {OpenAlex},
  doi = {10.1136/bmj.h6019},
  url = {https://doi.org/10.1136/bmj.h6019}
}

RIS

TY  - JOUR
TI  - Comparative benefits and harms of second generation antidepressants and cognitive behavioral therapies in initial treatment of major depressive disorder: systematic review and meta-analysis
AU  - Amick, Halle R
AU  - Gartlehner, Gerald
AU  - Gaynes, Bradley N.
AU  - Forneris, Catherine A
AU  - Asher, Gary
AU  - Morgan, Laura C
AU  - Coker‐Schwimmer, Emmanuel
AU  - Boland, Erin
AU  - Lux, Linda J
AU  - Gaylord, Susan
AU  - Bann, Carla
AU  - Pierl, Christiane Barbara
AU  - Lohr, Kathleen N
PY  - 2015
PB  - OpenAlex
DO  - 10.1136/bmj.h6019
UR  - https://doi.org/10.1136/bmj.h6019
ER  -

APA

Amick, H. R., Gartlehner, G., Gaynes, B. N., Forneris, C. A., Asher, G., Morgan, L. C., Coker‐Schwimmer, E., Boland, E., Lux, L. J., Gaylord, S., Bann, C., Pierl, C. B., & Lohr, K. N. (2015). Comparative benefits and harms of second generation antidepressants and cognitive behavioral therapies in initial treatment of major depressive disorder: systematic review and meta-analysis. OpenAlex. https://doi.org/10.1136/bmj.h6019

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