Baseline Functional Connectivity of the Mesolimbic, Salience, and Sensorimotor Systems Predicts Responses to Psychological Therapies for Chronic Low Back Pain With Comorbid Depression: A Functional MRI Study

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This fMRI study investigates how baseline functional connectivity in the mesolimbic, salience, and sensorimotor systems predicts responses to acceptance and commitment therapy or behavioral activation for depression in women with chronic low back pain and comorbid depression. The authors correlate resting-state connectivity patterns with changes in pain intensity, depression, and psychological inflexibility following eight weeks of treatment. The resource describes findings suggesting that specific neural biomarkers may help distinguish the underlying mechanisms of different cognitive behavioral therapies.

ID
0128098e3f754afc
Source org
PubMed Central
Author
Sonia Medina (King's College London), Carlos G. Forero (Universitat Internacional de Catalunya), Juan P. Sanabria‐Mazo (Parc Sanitari Sant Joan de Déu), Carla Rodríguez‐Freire (Parc Sanitari Sant Joan de Déu), Jaime Navarrete (Parc Sanitari Sant Joan de Déu), Owen O’Daly (King's College London), Matthew A. Howard (King's College London), Juan V. Luciano (Universitat Autònoma de Barcelona)
Published
2025-02-28
OA status
gold
DOI
10.1002/brb3.70380
PMID
Not recorded
PMCID
Not recorded
Citations
2

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BibTeX

@article{allodium:0128098e3f754afc,
  title = {Baseline Functional Connectivity of the Mesolimbic, Salience, and Sensorimotor Systems Predicts Responses to Psychological Therapies for Chronic Low Back Pain With Comorbid Depression: A Functional MRI Study},
  author = {Sonia Medina and Carlos G. Forero and Juan P. Sanabria‐Mazo and Carla Rodríguez‐Freire and Jaime Navarrete and Owen O’Daly and Matthew A. Howard and Juan V. Luciano},
  year = {2025},
  journal = {PubMed Central},
  doi = {10.1002/brb3.70380},
  url = {https://doi.org/10.1002/brb3.70380}
}

RIS

TY  - JOUR
TI  - Baseline Functional Connectivity of the Mesolimbic, Salience, and Sensorimotor Systems Predicts Responses to Psychological Therapies for Chronic Low Back Pain With Comorbid Depression: A Functional MRI Study
AU  - Medina, Sonia
AU  - Forero, Carlos G.
AU  - Sanabria‐Mazo, Juan P.
AU  - Rodríguez‐Freire, Carla
AU  - Navarrete, Jaime
AU  - O’Daly, Owen
AU  - Howard, Matthew A.
AU  - Luciano, Juan V.
PY  - 2025
PB  - PubMed Central
DO  - 10.1002/brb3.70380
UR  - https://doi.org/10.1002/brb3.70380
ER  -

APA

Medina, S., Forero, C. G., Sanabria‐Mazo, J. P., Rodríguez‐Freire, C., Navarrete, J., O’Daly, O., Howard, M. A., & Luciano, J. V. (2025). Baseline Functional Connectivity of the Mesolimbic, Salience, and Sensorimotor Systems Predicts Responses to Psychological Therapies for Chronic Low Back Pain With Comorbid Depression: A Functional MRI Study. PubMed Central. https://doi.org/10.1002/brb3.70380

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