IL-8 and IL-1RA serum levels predicting depression treatment response in 6-week follow-up

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This study examines whether baseline serum levels of interleukin-8 (IL-8) and interleukin-1 receptor antagonist (IL-1Ra) predict treatment response in 242 patients with major depressive disorder undergoing behavioral activation therapy. The research compares these inflammatory markers against changes in depression scores over a six-week period, controlling for factors such as age, BMI, and alcohol use. The findings suggest that higher baseline levels of IL-8 and IL-1Ra are associated with a smaller relative improvement in symptoms, particularly among patients with milder depression.

ID
012ea729b25248d4
Source org
PubMed Central
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DOI
10.1017/neu.2025.10027
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BibTeX

@article{allodium:012ea729b25248d4,
  title = {IL-8 and IL-1RA serum levels predicting depression treatment response in 6-week follow-up},
  journal = {PubMed Central},
  doi = {10.1017/neu.2025.10027},
  url = {https://doi.org/10.1017/neu.2025.10027}
}

RIS

TY  - JOUR
TI  - IL-8 and IL-1RA serum levels predicting depression treatment response in 6-week follow-up
PB  - PubMed Central
DO  - 10.1017/neu.2025.10027
UR  - https://doi.org/10.1017/neu.2025.10027
ER  -

APA

IL-8 and IL-1RA serum levels predicting depression treatment response in 6-week follow-up. (n.d.). PubMed Central. https://doi.org/10.1017/neu.2025.10027

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