Change and sustained recovery in defense mechanisms and depression in a pilot study of antidepressant medications plus up to 18 months of psychotherapy for recurrent major depression

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This pilot study examines the relationship between changes in depressive defense mechanisms and symptom reduction among thirty adults with recurrent major depression treated with antidepressants and up to 18 months of CBT, dynamic, or supportive psychotherapy. The resource reports significant decreases in depressive symptoms and improvements in overall defensive functioning over a 4.5-year follow-up period. It suggests that depressive defenses may serve as mediators of treatment effects and highlights their potential clinical utility for identifying ongoing risk.

ID
174fffcbec2a4ed7
Source org
PubMed Central
Author
John Christopher Perry (Jewish General Hospital), Claire J. Starrs (Jewish General Hospital), Trent Semeniuk (Jewish General Hospital), Elisabeth Banon (Jewish General Hospital), Ruta Westreich (Jewish General Hospital)
Published
2025-12-31
OA status
gold
DOI
10.4081/ripppo.2025.885
PMID
Not recorded
PMCID
Not recorded
Citations
0

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BibTeX

@article{allodium:174fffcbec2a4ed7,
  title = {Change and sustained recovery in defense mechanisms and depression in a pilot study of antidepressant medications plus up to 18 months of psychotherapy for recurrent major depression},
  author = {John Christopher Perry and Claire J. Starrs and Trent Semeniuk and Elisabeth Banon and Ruta Westreich},
  year = {2025},
  journal = {PubMed Central},
  doi = {10.4081/ripppo.2025.885},
  url = {https://doi.org/10.4081/ripppo.2025.885}
}

RIS

TY  - JOUR
TI  - Change and sustained recovery in defense mechanisms and depression in a pilot study of antidepressant medications plus up to 18 months of psychotherapy for recurrent major depression
AU  - Perry, John Christopher
AU  - Starrs, Claire J.
AU  - Semeniuk, Trent
AU  - Banon, Elisabeth
AU  - Westreich, Ruta
PY  - 2025
PB  - PubMed Central
DO  - 10.4081/ripppo.2025.885
UR  - https://doi.org/10.4081/ripppo.2025.885
ER  - 

APA

Perry, J. C., Starrs, C. J., Semeniuk, T., Banon, E., & Westreich, R. (2025). Change and sustained recovery in defense mechanisms and depression in a pilot study of antidepressant medications plus up to 18 months of psychotherapy for recurrent major depression. PubMed Central. https://doi.org/10.4081/ripppo.2025.885

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