Feasibility and user evaluation of HopeBot: An LLM-powered conversational chatbot for depression screening

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Overview

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This paper describes HopeBot, an LLM-powered chatbot designed to administer the PHQ-9 depression screening questionnaire through conversational interaction rather than static forms. The resource details a feasibility study involving 132 adults who completed both self-administered and chatbot-assisted assessments, reporting high score concordance and positive user feedback regarding clarity and tone. It is intended for readers interested in digital mental health tools, specifically those exploring scalable, interactive screening adjuncts.

ID
2f5354f04e4e4b64
Source org
PubMed Central
Author
Zhijun Guo (Farr Institute), Alvina Lai (Farr Institute), Julia Ive (Farr Institute), Alexandru Petcu (Lancashire Care NHS Foundation Trust), Yutong Wang (Farr Institute), Luyuan Qi (Farr Institute), Johan H. Thygesen (Farr Institute), Kezhi Li (University College London Hospitals NHS Foundation Trust)
Published
2026-06-25
OA status
gold
DOI
10.1371/journal.pdig.0001446
PMID
Not recorded
PMCID
Not recorded
Citations
0

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BibTeX

@article{allodium:2f5354f04e4e4b64,
  title = {Feasibility and user evaluation of HopeBot: An LLM-powered conversational chatbot for depression screening},
  author = {Zhijun Guo and Alvina Lai and Julia Ive and Alexandru Petcu and Yutong Wang and Luyuan Qi and Johan H. Thygesen and Kezhi Li},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1371/journal.pdig.0001446},
  url = {https://doi.org/10.1371/journal.pdig.0001446}
}

RIS

TY  - JOUR
TI  - Feasibility and user evaluation of HopeBot: An LLM-powered conversational chatbot for depression screening
AU  - Guo, Zhijun
AU  - Lai, Alvina
AU  - Ive, Julia
AU  - Petcu, Alexandru
AU  - Wang, Yutong
AU  - Qi, Luyuan
AU  - Thygesen, Johan H.
AU  - Li, Kezhi
PY  - 2026
PB  - PubMed Central
DO  - 10.1371/journal.pdig.0001446
UR  - https://doi.org/10.1371/journal.pdig.0001446
ER  -

APA

Guo, Z., Lai, A., Ive, J., Petcu, A., Wang, Y., Qi, L., Thygesen, J. H., & Li, K. (2026). Feasibility and user evaluation of HopeBot: An LLM-powered conversational chatbot for depression screening. PubMed Central. https://doi.org/10.1371/journal.pdig.0001446

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