Integration of stepped care for perinatal mood and anxiety disorders among women attending maternal and child health clinics in Kenya: Protocol for a cluster randomized controlled trial

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This protocol outlines a cluster randomized controlled trial evaluating a stepped-care model for perinatal mood and anxiety disorders in Kenyan maternal health clinics. The study involves screening pregnant women and providing Problem Management Plus counseling by lay providers, with telepsychiatry available for severe cases. It aims to assess clinical outcomes, service delivery metrics, and implementation factors across 2,970 participants.

ID
52912b4568574519
Source org
PubMed Central
Author
Agnes Karingo Karume (Kenyatta National Hospital), Nancy Ngumbau (Kenyatta National Hospital), Linnet Ongeri (Kenya Medical Research Institute), Asterico Neema (Kenyatta National Hospital), Anne Kaggiah (Kenyatta National Hospital), David Owaga (Kenyatta National Hospital), Catherine Maina (Kenyatta National Hospital), Clinton Ndambuki (Kenyatta National Hospital), Y. Wang (University of Washington), Lincoln Pothan (University of Washington), Alexandra Rose (University of Washington), Anna Larsen (University of Washington), Sarah Masyuko (University of Washington), Barbra A. Richardson (University of Washington), Anjuli D. Wagner (University of Washington), Amritha Bhat (University of Washington), Keshet Ronen (University of Washington), John Kinuthia (Kenyatta National Hospital)
Published
2026-06-11
OA status
gold
DOI
10.1371/journal.pone.0349732
PMID
Not recorded
PMCID
Not recorded
Citations
0

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BibTeX

@article{allodium:52912b4568574519,
  title = {Integration of stepped care for perinatal mood and anxiety disorders among women attending maternal and child health clinics in Kenya: Protocol for a cluster randomized controlled trial},
  author = {Agnes Karingo Karume and Nancy Ngumbau and Linnet Ongeri and Asterico Neema and Anne Kaggiah and David Owaga and Catherine Maina and Clinton Ndambuki and Y. Wang and Lincoln Pothan and Alexandra Rose and Anna Larsen and Sarah Masyuko and Barbra A. Richardson and Anjuli D. Wagner and Amritha Bhat and Keshet Ronen and John Kinuthia},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1371/journal.pone.0349732},
  url = {https://doi.org/10.1371/journal.pone.0349732}
}

RIS

TY  - JOUR
TI  - Integration of stepped care for perinatal mood and anxiety disorders among women attending maternal and child health clinics in Kenya: Protocol for a cluster randomized controlled trial
AU  - Karume, Agnes Karingo
AU  - Ngumbau, Nancy
AU  - Ongeri, Linnet
AU  - Neema, Asterico
AU  - Kaggiah, Anne
AU  - Owaga, David
AU  - Maina, Catherine
AU  - Ndambuki, Clinton
AU  - Wang, Y.
AU  - Pothan, Lincoln
AU  - Rose, Alexandra
AU  - Larsen, Anna
AU  - Masyuko, Sarah
AU  - Richardson, Barbra A.
AU  - Wagner, Anjuli D.
AU  - Bhat, Amritha
AU  - Ronen, Keshet
AU  - Kinuthia, John
PY  - 2026
PB  - PubMed Central
DO  - 10.1371/journal.pone.0349732
UR  - https://doi.org/10.1371/journal.pone.0349732
ER  -

APA

Karume, A. K., Ngumbau, N., Ongeri, L., Neema, A., Kaggiah, A., Owaga, D., Maina, C., Ndambuki, C., Wang, Y., Pothan, L., Rose, A., Larsen, A., Masyuko, S., Richardson, B. A., Wagner, A. D., Bhat, A., Ronen, K., & Kinuthia, J. (2026). Integration of stepped care for perinatal mood and anxiety disorders among women attending maternal and child health clinics in Kenya: Protocol for a cluster randomized controlled trial. PubMed Central. https://doi.org/10.1371/journal.pone.0349732

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