Examining the relationship between pre-treatment anhedonia and treatment outcomes in individuals with anxiety or depression: A systematic review

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This systematic review synthesizes literature on how pre-treatment anhedonia relates to treatment response in individuals with anxiety or unipolar depressive disorders receiving psychotherapy, pharmacotherapy, or neuromodulation. The authors report inconsistent findings across 28 studies, noting that some associate higher anhedonia with worse outcomes while others find no significant relationship or mixed results. The resource concludes that definitive conclusions are currently limited by methodological heterogeneity and inadequate power in existing secondary analyses.

ID
7feccb23d92645c4
Source org
PubMed Central
Author
Madeleine Rassaby (San Diego State University), Isabella Spaulding (San Diego State University), Murray B. Stein (San Diego State University), Charles T. Taylor (San Diego State University)
Published
2025-11-21
OA status
hybrid
DOI
10.1016/j.jad.2025.120733
PMID
Not recorded
PMCID
Not recorded
Citations
1

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BibTeX

@article{allodium:7feccb23d92645c4,
  title = {Examining the relationship between pre-treatment anhedonia and treatment outcomes in individuals with anxiety or depression: A systematic review},
  author = {Madeleine Rassaby and Isabella Spaulding and Murray B. Stein and Charles T. Taylor},
  year = {2025},
  journal = {PubMed Central},
  doi = {10.1016/j.jad.2025.120733},
  url = {https://doi.org/10.1016/j.jad.2025.120733}
}

RIS

TY  - JOUR
TI  - Examining the relationship between pre-treatment anhedonia and treatment outcomes in individuals with anxiety or depression: A systematic review
AU  - Rassaby, Madeleine
AU  - Spaulding, Isabella
AU  - Stein, Murray B.
AU  - Taylor, Charles T.
PY  - 2025
PB  - PubMed Central
DO  - 10.1016/j.jad.2025.120733
UR  - https://doi.org/10.1016/j.jad.2025.120733
ER  -

APA

Rassaby, M., Spaulding, I., Stein, M. B., & Taylor, C. T. (2025). Examining the relationship between pre-treatment anhedonia and treatment outcomes in individuals with anxiety or depression: A systematic review. PubMed Central. https://doi.org/10.1016/j.jad.2025.120733

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