Positive Affect Treatment for Depression, Anxiety, and Low Positive Affect

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This randomized clinical trial compares Positive Affect Treatment (PAT) and Negative Affect Treatment (NAT) in 98 adults with low positive affect and depression or anxiety. The study evaluates whether PAT engages reward systems more effectively and if changes in reward and threat processing mediate clinical outcomes. Results indicate that PAT led to greater improvements in clinical status than NAT, with self-reported measures of reward and threat mediation identified as key mechanisms.

ID
4fc07ae97e844a54
Source org
PubMed Central
Author
Alicia E. Meuret (Southern Methodist University), David Rosenfield (Southern Methodist University), Emily Wang (Southern Methodist University), Christina M. Hough (University of California, Los Angeles), Thomas Ritz (Southern Methodist University), Michelle G. Craske (University of California, Los Angeles)
Published
2026-04-24
OA status
gold
DOI
10.1001/jamanetworkopen.2026.7403
PMID
Not recorded
PMCID
Not recorded
Citations
1

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BibTeX

@article{allodium:4fc07ae97e844a54,
  title = {Positive Affect Treatment for Depression, Anxiety, and Low Positive Affect},
  author = {Alicia E. Meuret and David Rosenfield and Emily Wang and Christina M. Hough and Thomas Ritz and Michelle G. Craske},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1001/jamanetworkopen.2026.7403},
  url = {https://doi.org/10.1001/jamanetworkopen.2026.7403}
}

RIS

TY  - JOUR
TI  - Positive Affect Treatment for Depression, Anxiety, and Low Positive Affect
AU  - Meuret, Alicia E.
AU  - Rosenfield, David
AU  - Wang, Emily
AU  - Hough, Christina M.
AU  - Ritz, Thomas
AU  - Craske, Michelle G.
PY  - 2026
PB  - PubMed Central
DO  - 10.1001/jamanetworkopen.2026.7403
UR  - https://doi.org/10.1001/jamanetworkopen.2026.7403
ER  -

APA

Meuret, A. E., Rosenfield, D., Wang, E., Hough, C. M., Ritz, T., & Craske, M. G. (2026). Positive Affect Treatment for Depression, Anxiety, and Low Positive Affect. PubMed Central. https://doi.org/10.1001/jamanetworkopen.2026.7403

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