Life experiences of humiliation, entrapment, and frontoparietal-cerebellar connectivity predict adolescent anxiety and depression symptoms

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This longitudinal study examines how specific life stressors and brain connectivity patterns relate to anxiety and depression in adolescents enriched for these disorders. The authors analyze the impact of stressor characteristics like humiliation and entrapment, alongside resting-state functional connectivity between the frontoparietal network and the left cerebellum. Results indicate that exposure to humiliation and entrapment predicts internalizing symptoms over time, with brain connectivity serving as a potential marker for these issues.

ID
e6f38d8f35664d25
Source org
PubMed Central
Author
Yueyue Qu (Yale University), Sidhant Chopra (The University of Melbourne), Shijie Qu (Yale University), Carrisa V. Cocuzza (Rutgers Sexual and Reproductive Health and Rights), Loïc Labache (Rutgers Sexual and Reproductive Health and Rights), Clemens Bauer (Massachusetts Institute of Technology), Francesca Morfini (Harvard University), Susan Whitfield-Gabrieli (Massachusetts Institute of Technology), George M. Slavich (University of California, Los Angeles), Jutta Joormann (Yale University), Avram J. Holmes (Rutgers Sexual and Reproductive Health and Rights)
Published
2026-01-01
OA status
hybrid
DOI
10.1017/S0033291726103699
PMID
Not recorded
PMCID
Not recorded
Citations
0

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BibTeX

@article{allodium:e6f38d8f35664d25,
  title = {Life experiences of humiliation, entrapment, and frontoparietal-cerebellar connectivity predict adolescent anxiety and depression symptoms},
  author = {Yueyue Qu and Sidhant Chopra and Shijie Qu and Carrisa V. Cocuzza and Loïc Labache and Clemens Bauer and Francesca Morfini and Susan Whitfield-Gabrieli and George M. Slavich and Jutta Joormann and Avram J. Holmes},
  year = {2026},
  journal = {PubMed Central},
  doi = {10.1017/S0033291726103699},
  url = {https://doi.org/10.1017/S0033291726103699}
}

RIS

TY  - JOUR
TI  - Life experiences of humiliation, entrapment, and frontoparietal-cerebellar connectivity predict adolescent anxiety and depression symptoms
AU  - Qu, Yueyue
AU  - Chopra, Sidhant
AU  - Qu, Shijie
AU  - Cocuzza, Carrisa V.
AU  - Labache, Loïc
AU  - Bauer, Clemens
AU  - Morfini, Francesca
AU  - Whitfield-Gabrieli, Susan
AU  - Slavich, George M.
AU  - Joormann, Jutta
AU  - Holmes, Avram J.
PY  - 2026
PB  - PubMed Central
DO  - 10.1017/S0033291726103699
UR  - https://doi.org/10.1017/S0033291726103699
ER  -

APA

Qu, Y., Chopra, S., Qu, S., Cocuzza, C. V., Labache, L., Bauer, C., Morfini, F., Whitfield-Gabrieli, S., Slavich, G. M., Joormann, J., & Holmes, A. J. (2026). Life experiences of humiliation, entrapment, and frontoparietal-cerebellar connectivity predict adolescent anxiety and depression symptoms. PubMed Central. https://doi.org/10.1017/S0033291726103699

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